Left Atrial Myxoma

Schiele, Sandra; Maurer, Sabine; Pujol, C.; Vitanova, Keti; Weirich, Gregor; Meierhofer, Christian; Voß, Bernhard; Ewert, Peter; Tutarel, Oktay

doi:10.1161/circimaging.118.008820

Cited by 11 publications

(14 citation statements)

References 3 publications

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“…Whilst leaflet dysfunction due to retraction, restriction, and atrophy probably due to prolonged pressure effects exerted by the mass requiring bioprosthetic valve implantation has been described, 8 most reports describe that the valve leaflets themselves are normal, with favourable effects of annuloplasty ring implantation. 9 Subsequent follow-up imaging in this case demonstrated right ventricular remodelling following correction of tricuspid regurgitation, accompanied by resolution of symptoms.…”

Section: Discussionmentioning

confidence: 61%

An enormous right atrial myxoma highlights the role of echocardiography in heart failure pathways: a case report

Straw

Sengupta

Gantenby

et al. 2022

European Heart Journal - Case Reports

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Background Myxomata are rare, benign, primary tumours of the heart which can present with a variety of symptoms depending on size, location, and mobility. Here we report a case of enormous right atrial myxoma, obliterating the right atrial and right ventricular cavities presenting with symptoms of heart failure. Case summary A 66-year-old, Caucasian female presented to primary care with symptoms of right heart failure and was found to have elevated N-terminal pro B-type natriuretic peptide of 2829 ng/L (normal value <125ng/L). The patient was referred for urgent evaluation to the integrated heart failure service at our institution. Echocardiography revealed an enormous mobile mass attached to the right atrial septum, extending into the right ventricle and inferior vena cava measuring 90x42mm. The patient underwent urgent surgical resection. Perioperative transoesophageal echocardiography demonstrated severe tricuspid regurgitation, which was treated with tricuspid annuloplasty ring. The patient made an uneventful recovery and was discharged. Subsequent imaging showed a reduction in right ventricular dimensions and improved systolic function. Discussion This case serves to remind us of the critical role of echocardiography in the diagnosis and management of people with breathlessness and raised natriuretic peptides. All currently applied therapies for heart failure are limited to those with reduced ejection fraction, therefore timely and accurate diagnosis is critical. Moreover, as in this case, echocardiography can also identify other features of critical relevance to patient care.

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Section: Discussionmentioning

confidence: 61%

An enormous right atrial myxoma highlights the role of echocardiography in heart failure pathways: a case report

Straw

Sengupta

Gantenby

et al. 2022

European Heart Journal - Case Reports

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“…This can lead to symptoms such as shortness of breath, syncope, and chest pain. 7 Second, they may grow large and be locally invasive, resulting in heart failure or arrhythmias, such as atrial fibrillation. 6 Third, they can embolize and travel to various organs of the body, either in part or whole.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical resection of the tumor, its margins, and any embolic masses to the lung is the criterion standard of treatment for right atrial myxomas. 4,7,8 No specific pharmacologic therapies have been identified that target these tumors directly. Aspirin or anticoagulation therapies have not shown benefit for managing these tumors.…”

Section: Discussionmentioning

confidence: 99%

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A Middle-aged Man With Sharp Chest Pain

Gaba

Luber

2021

JAMA Cardiol

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“…Patients may be asymptomatic until the condition reaches an advanced stage. The symptoms of cardiac sarcomas include dyspnea, orthopnea, paroxysmal nocturnal dyspnea, or lower extremity edema [9]. Patients with advanced stages of cancer can also present with symptoms of metastatic disease.…”

Section: Primary Cardiac Tumormentioning

confidence: 99%

Primary Cardiac Intimal Sarcoma with Extensive Left Atrial Involvement Treated with Cryoablation

2022

J Surg

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A primary cardiac tumor is extremely rare. The majority of primary cardiac tumors are benign, and approximately onequarter are malignant. The most common type of cardiac tumor is cardiac myxoma, which is usually located in the left atrium. Aside from the above, the majority of these malignant tumors are sarcomas, which can be distinguished by their different histologies. However, the differential diagnosis between benign myxomas and malignant sarcomas might be challenging in certain cases, and a high index of clinical suspicion and vimentin staining can be useful in making the diagnosis. In this case report, we present a young female who received an operation for a tumor of the left atrium that was initially diagnosed as a myxoma but later recurred as a myxofibrosarcoma. As a consequence of the immunoreactive results of MDM2 amplification, cardiac intimal sarcoma was finally diagnosed. It is notable that surgical removal of the primary tumor with extensive cryoablation of horizontal tumor spreading using a cryoballoon and cryoablation probe, which are initially designed for pulmonary vein isolation and Maze procedure, incorporated with postoperative radiotherapy, chemotherapy, and surgery to remove the costal bone metastasis effectively prevents the disease from relapsing and recurrences.

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Left Atrial Myxoma

Cited by 11 publications

References 3 publications

An enormous right atrial myxoma highlights the role of echocardiography in heart failure pathways: a case report

An enormous right atrial myxoma highlights the role of echocardiography in heart failure pathways: a case report

A Middle-aged Man With Sharp Chest Pain

Primary Cardiac Intimal Sarcoma with Extensive Left Atrial Involvement Treated with Cryoablation

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