Left Atrial Expansion Index Predicts Atrial Fibrillation in Dyspnea

Abstract

The LA expansion index is associated with the presence of AF, and a reduced LA expansion index has a strong association with persistent AF.

Diastolic Heart Failure Predicted by Left Atrial Expansion Index in Patients with Severe Diastolic Dysfunction

“…Af was the leading predisposing factor for HFpEF events in this study. In line with our prior study [ 27 ], LAEI was an independent predictor of further occurrence of Af ( S3 Table ). Atrial fibrosis is an underlying cause of the occurrence and persistence of Af [ 28 ].…”

Left atrial volume and function in patients with white-coat hypertension assessed by real-time three-dimensional echocardiography

“…LA systolic functions play a pivotal role during LV filling as suggested by the increased LA active emptying volume in patients with WCH. The LA expansion index reflects both LA stretch ability and LV filling status [27]. LA function shows a significant independent correlation with LV diastolic dysfunction, cardiac arrhythmias, and arterial stiffness in most categories of patients compared with LA volume [28].…”

Lung Deflation and Cardiovascular Structure and Function in Chronic Obstructive Pulmonary Disease. A Randomized Controlled Trial

“…On a population level, one SD decrement (11 ml/m 2 ) in RVEDVI has been associated with a 12% increase in the risk of dyspnea after adjustment for spirometric measurements and CT-defined emphysema (15). Furthermore, increases in cardiac output are associated with improvements in walking intensity across all severities of COPD, whereas reduced atrial EF, independent of atrial size, predicts the development of atrial fibrillation in patients with dyspnea (16)(17)(18). The ability to modify cardiac morphology and function does therefore seem to independently impact on relevant clinical and patientcentered outcomes, and highlights the importance of identifying and optimally treating this "lung-deflator" clinical phenotype (19).…”