Leech on External Thrombosed Hemorrhoids

Ag, Ravishankar; Rao, Ravi S; Mahesh, T S; Subrahmanya, Poornima; Krishnamurthy, Madhuram

doi:10.7897/2230-8407.041112

Cited by 3 publications

(2 citation statements)

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“…Ravi Shankar et al concluded that leech therapy was effective in treating thrombosed hemorrhoids, resulting in immediate reduction in swelling, pain, and tenderness. 25 According to Rajesh Gupta et al, leech therapy effectively treats thrombosed hemorrhoids by providing analgesic and thrombolytic activity. 26 Zarnigar et al demonstrated the efficacy of leech therapy in managing varicose vein symptoms and preventing complications associated with varicose veins.…”

Section: Leech Therapy In Contemporary Healthcarementioning

confidence: 99%

A Review on Leech Therapy (Ta‘liq Al-‘Alaq): Historical Perspective and Potential Applications in Modern Medicine

Ahmad¹,

Khan²,

M³

2023

J Biol Sci Opin

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The Unani system of medicine, rooted in the principle of balancing the body's humours, has long believed that imbalances in these humours lead to various illnesses. Restoring the equilibrium of humours is considered vital for promoting good health. Classical texts on Unani medicine delineate three distinct methods for treating diseases: pharmacotherapy, regimenal therapy, and surgery. Among regimenal therapies, leech therapy (Ta‘liq al-‘Alaq) has emerged as an exceptionally effective and distinctive method of bloodletting. By utilizing this traditional technique, leech therapy facilitates the evacuation of morbid humours from the body, addressing the underlying cause of ailments. Over time, leech therapy has transitioned from a traditional practice to gaining recognition as a valuable treatment modality in evidence-based medicine. The safety and efficacy of leech therapy have been supported by clinical reports and pharmacological experiments, demonstrating its potential in healing chronic wounds and managing various ailments. This study explores the historical perspective and potential applications of leech therapy in modern medicine.

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Section: Leech Therapy In Contemporary Healthcarementioning

confidence: 99%

A Review on Leech Therapy (Ta‘liq Al-‘Alaq): Historical Perspective and Potential Applications in Modern Medicine

Ahmad¹,

Khan²,

M³

2023

J Biol Sci Opin

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“…There has been an upsurge in the use of natural polymers for the numerous pharmaceutical formulations [9,10]. Biogenic polymers are used in several pharmaceutical fields in various forms such as microspheres, nanomatrix, liquid formulations as wells as transdermal or buccal films [11,12].…”

Section: Introductionmentioning

confidence: 99%

Facile synthesis of antibiotic encapsulated biopolymeric okra mucilage nanoparticles: molecular docking, in vitro stability and functional evaluation

Masum¹,

Pal²,

Saha³

et al. 2020

Adv. Nat. Sci: Nanosci. Nanotechnol.

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The biocompatible, biodegradable okra mucilage nanoparticles (MNPs) were synthesised by a facile synthesis process and characterised by employing XRD, FTIR and FESEM studies. These were then encapsulated with the antibiotics (streptomycin, ampicillin and kanamycin) which are widely used in several pathogenic conditions. These antibiotics are susceptible to functional degradation upon exposure to adverse conditions like high temperature, UV, etc. The encapsulation of antibiotics within the mucilage matrix was testified with the aid of x-ray diffraction (XRD), FTIR, UV-vis, dynamic light scattering (DLS) as well as molecular docking estimations. These mucilage nanoparticles were then encapsulated with antibiotics when applied against bacterial strains like Escherichia coli DH5α and Staphylococcus aureus. The results demonstrated augmented bactericidal activity in comparison to the bare form of antibiotics. Our results further depict that the encapsulation of these antibiotics within the mucilage nanoparticles enhances their functionalities and also stabilises these antibiotics in conditions like elevated temperature, UV exposure and prolonged storage. Additionally, Rhodamine-B a fluorescent dye was encapsulated within the okra mucilage nanoparticles and is readily internalised by the human lung fibroblast cells, WI-38. Thus, our findings implicate that these synthesised MNPs are truly multi and can emerge as a promising therapeutic intervention in the coming years.

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Clinical Efficacy of Medicinal Leech Therapy in Treating Third- and Fourth-Degree Hemorrhoids

Mobeen

Ahmad

Quamri

et al. 2021

Journal of Coloproctology

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Objectives Hemorrhoids are characterized by bleeding, mucous discharge, itching, pain, and prolapse. This condition is known as bawaseer in Unani medicine, and Hirudinaria granulosa has been used for its treatment in Irsal-e Alaq, or medicinal leech therapy (MLT), for centuries. Hirudinaria granulosa with antithrombotic and antiinflammatory action is used in the treatment of chronic venous disease and hemorrhoids. The present study was aimed to investigate the efficacy of MLT in third and fourth-degree hemorrhoids. Methods A single-centre prospective, clinical trial with a pre and postanalysis design was conducted at the hospital of the National Institute of Unani Medicine. Twenty male and female patients, with a mean age of 38 years, presenting moderate symptoms assessed with the colorectal evaluation of clinical therapeutics scale (CORECTS) questionnaire were included in the study. Hirudinaria granulosa were applied around the pile mass for 15 minutes weekly, for 4 weeks. The efficacy of the treatment was measured by an objective and subjective assessment using the CORECTS. Results When analyzed by the clinician, MLT reduced the symptoms' severity score in the following domains: pain (55% improvement; p < 0.001); anorectal itching (30% improvement; p < 0.10); and bleeding (10% improvement; p < 0.7963). Significant improvement (p < 0.001) was reported in the CORECTS score in relation to pain (44.09% improvement; p < 0.001), itching (38.55% improvement; p < 0.001), swelling (44% improvement; p < 0.001), bleeding (17.28% improvement; p < 0.007), discomfort (34.01% improvement; p < 0.001), and wellbeing (32.35 %improvement; p < 0.001), giving an average overall opinion on the therapy of 4/10. Conclusion The results of the study albeit smaller in sample size show that MLT is an effective and safe therapeutic option in reducing the symptoms of 3rd and 4th degree haemorrhoids.

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Leech on External Thrombosed Hemorrhoids

Cited by 3 publications

References 0 publications

A Review on Leech Therapy (Ta‘liq Al-‘Alaq): Historical Perspective and Potential Applications in Modern Medicine

A Review on Leech Therapy (Ta‘liq Al-‘Alaq): Historical Perspective and Potential Applications in Modern Medicine

Facile synthesis of antibiotic encapsulated biopolymeric okra mucilage nanoparticles: molecular docking, in vitro stability and functional evaluation

Clinical Efficacy of Medicinal Leech Therapy in Treating Third- and Fourth-Degree Hemorrhoids

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