Lectin-Based Approaches to Analyze the Role of Glycans and Their Clinical Application in Disease
Hiroko Ideo,
Akiko Tsuchida,
Yoshio Takada
Abstract:Lectin-based approaches remain a valuable tool for analyzing glycosylation, especially when detecting cancer-related changes. Certain glycans function as platforms for cell communication, signal transduction, and adhesion. Therefore, the functions of glycans are important considerations for clinical aspects, such as cancer, infection, and immunity. Considering that the three-dimensional structure and multivalency of glycans are important factors for their function, their binding characteristics toward lectins … Show more
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