Lecithin-cholesterol acyltransferase activity during two types of protein malnutrition followed by balanced refeeding in the growing rat

Abstract

Our earlier studies (Meghelli-Bouchenak et al, 1987, 1989a Knipping (1986).In the T group (15% casein), a reduction in LACT activity with age was noted. The onset of both types of PM promoted the same significant decrease in LCAT activity (P < 0.05). At d 3 of BR, a significant rise was observed, which was more marked in group C (2% casein) than in group Gi (5% gluten).This study confirmed that HDL were resistant to PM and that their apoprotein and lipid composition was not significantly modified. Balanced refeeding involved a significant increase in apo AI. These results suggest that in spite of the reduction in LACT activity with both types of PM, HDL metabolism was not significantly impaired, this was due in part to a normal level of apo Al.