2013
DOI: 10.1007/s00104-012-2413-8
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Lebertransplantation mit postmortalen Organen

Abstract: Deceased donor liver transplantation is nowadays a routine procedure for the treatment of terminal liver failure and often represents the only chance of a cure. Under given optimal conditions excellent long-term results can be obtained with 15-year survival rates of well above 60 %.In Germany the outcome after liver transplantation has deteriorated since the introduction of an allocation policy, which is based on the medical urgency. At present 25 % of liver graft recipients die within the first year after tra… Show more

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Cited by 22 publications
(12 citation statements)
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“…We propose the definition of a quality catalogue that includes accuracy of reporting to AQUA, success rate represented by 1-year patient and graft survival data [15], incidence of re-transplantations and audit results. Certification of centers with an evaluated minimum standard infrastructure, structured education of transplant specialists and reconsideration of budgeting of transplant medicine are further important steps that need to be accomplished.…”
Section: Resultsmentioning
confidence: 99%
“…We propose the definition of a quality catalogue that includes accuracy of reporting to AQUA, success rate represented by 1-year patient and graft survival data [15], incidence of re-transplantations and audit results. Certification of centers with an evaluated minimum standard infrastructure, structured education of transplant specialists and reconsideration of budgeting of transplant medicine are further important steps that need to be accomplished.…”
Section: Resultsmentioning
confidence: 99%
“…The limited amount of donor organs led to the implementation of different liver allocation policies[ 10 , 11 ] and a more liberal acceptance of extended criteria donor (ECD) organs[ 12 , 13 ]. The implementation of Model for end-stage liver disease (MELD) allocation in 2006 within the Eurotransplant area has reduced waiting list mortality to about 10%[ 14 ], but has also increased the one-year mortality in many European centers, e.g ., at our center from 8.2% to about 17.4%[ 15 ]. Donor-recipient-matching has become crucial to achieving reasonable one year mortality[ 16 ] and acceptable waiting list mortality, especially when allocating marginal organs to progressively sicker recipients.…”
Section: Introductionmentioning
confidence: 99%
“…(1)(2)(3)(4)(5)(6)(7)(8)12) This study was also prompted by concerns over the outcomes after liver transplantation in Germany compared with those in the United States and the United Kingdom (14) that had become more apparent since the introduction of Model for End-Stage Liver Disease (MELD) score-based donor liver allocation policies in Germany at the end of 2006. (16)(17)(18) The patient survival rate after 1 year is currently only 72% in Germany, which is 20% lower than in the United States and the United Kingdom; Germany has more transplant centers and fewer organ donors per capita. (14) In the United Kingdom, there is a widely accepted and applied consensus to transplant only those patients who have a realistic chance of surviving more than 5 years after transplantation, so centers are trying to balance need with utility and benefit.…”
mentioning
confidence: 99%