Learning related activation of somatosensory cortex by an auditory stimulus recorded with magnetoencephalography

Moses, Sandra N.; Bardouille, Timothy; Brown, Tanya M.; Roß, Bernhard; McIntosh, Anthony R.

doi:10.1016/j.neuroimage.2010.06.005

Cited by 8 publications

(16 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Likewise, Pizzagalli and colleagues () found amplitude enhancements over primary auditory cortex occurring within 100 ms following presentation of a visual CS + that was previously paired with an auditory US. In other studies, a visual (Wik, Elbert, Fredrikson, Hoke, & Ross, ) or an auditory (Moses, Bardouille, Brown, Ross, & McIntosh, ) CS +, compared to the CS‐, increased activation of the primary somatosensory cortex when the electrodermal US was omitted. Cross‐modal conditioned brain responses disappear following extinction learning (Wik, Elbert, Fredrikson, Hoke, & Ross, ).…”

Section: Macroscopic Correlates Of Fear Conditioning: Human Eeg/meg Smentioning

confidence: 88%

Acquired fears reflected in cortical sensory processing: A review of electrophysiological studies of human classical conditioning

2012

View full text Add to dashboard Cite

The capacity to associate neutral stimuli with affective value is an important survival strategy that can be accomplished by cell assemblies obeying Hebbian learning principles. In the neuroscience laboratory, classical fear conditioning has been extensively used as a model to study learning related changes in neural structure and function. Here, we review the effects of classical fear conditioning on electromagnetic brain activity in humans, focusing on how sensory systems adapt to changing fear-related contingencies. By considering spatio-temporal patterns of mass neuronal activity we illustrate a range of cortical changes related to a retuning of neuronal sensitivity to amplify signals consistent with fear-associated stimuli at the cost of other sensory information. Putative mechanisms that may underlie fear-associated plasticity at the level of the sensory cortices are briefly considered and several avenues for future work are outlined.

show abstract

Section: Macroscopic Correlates Of Fear Conditioning: Human Eeg/meg Smentioning

confidence: 88%

Acquired fears reflected in cortical sensory processing: A review of electrophysiological studies of human classical conditioning

2012

View full text Add to dashboard Cite

show abstract

“…Here, we used magnetoencephalography (MEG) (11,12) to address human auditory plasticity in an aversive classicalconditioning paradigm (1)(2)(3), focusing on the well-known, successive, auditory-evoked field components P1m, N1m, and P2m (13,14). Other human EEG or MEG work on conditioning typically used a visual rather than auditory CS + (15)(16)(17), but see ref.…”

mentioning

confidence: 99%

“…Other human EEG or MEG work on conditioning typically used a visual rather than auditory CS + (15)(16)(17), but see ref. 11).…”

mentioning

confidence: 99%

Plasticity of human auditory-evoked fields induced by shock conditioning and contingency reversal

Kluge

Bauer

Leff

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

We used magnetoencephalography (MEG) to assess plasticity of human auditory cortex induced by classical conditioning and contingency reversal. Participants listened to random sequences of high or low tones. A first baseline phase presented these without further associations. In phase 2, one of the frequencies (CS + ) was paired with shock on half its occurrences, whereas the other frequency (CS − ) was not. In phase 3, the contingency assigning CS + and CS − was reversed. Conditioned pupil dilation was observed in phase 2 but extinguished in phase 3. MEG revealed that, during phase-2 initial conditioning, the P1m, N1m, and P2m auditory components, measured from sensors over auditory temporal cortex, came to distinguish between CS + and CS − . After contingency reversal in phase 3, the later P2m component rapidly reversed its selectivity (unlike the pupil response) but the earlier P1m did not, whereas N1m showed some new learning but not reversal. These results confirm plasticity of human auditory responses due to classical conditioning, but go further in revealing distinct constraints on different levels of the auditory hierarchy. The later P2m component can reverse affiliation immediately in accord with an updated expectancy after contingency reversal, whereas the earlier auditory components cannot. These findings indicate distinct cognitive and emotional influences on auditory processing.

show abstract

“…Specifically, they asked whether the presence of memories about an object changes the way the brain responds at the time of initial perception, or whether the changes occur following initial perceptual processing at a time when memory processing is traditionally thought to occur. In contrast to Moses et al (2005Moses et al ( , 2007Moses et al ( , 2010, in which memory acquisition occurred within the experimental session, Ryan et al (2008) used a paradigm in which the ''previous learning episodes'' occurred in real life prior to the experiment, and in which the learned associated information was not presented at any time during the study and was not needed in order to complete the task given to the participants. Thus, they could ask whether early changes in neural activity actually represent a long-term change in perceptual processing, or whether they are merely a short-lived artificial change induced only in the laboratory as a result of the particular experimental procedures.…”

Section: When Does Memory Modulate Primary Sensory Activity?mentioning

confidence: 99%

“…Using MEG, Moses et al (2010) investigated the conditions under which extra-hippocampal systems can facilitate performance on what has traditionally been shown to be a hippocampal-dependent relational memory task: transverse patterning. (e.g.…”

Section: Imaging the Potential For Compensationmentioning

confidence: 99%

Dynamic Imaging of Deep Brain Structures with MEG: Contributions to Understanding Human Memory

Moses¹,

Hanlon²,

Ryan³

2011

Magnetoencephalography

View full text Add to dashboard Cite

Learning related activation of somatosensory cortex by an auditory stimulus recorded with magnetoencephalography

Cited by 8 publications

References 65 publications

Acquired fears reflected in cortical sensory processing: A review of electrophysiological studies of human classical conditioning

Acquired fears reflected in cortical sensory processing: A review of electrophysiological studies of human classical conditioning

Plasticity of human auditory-evoked fields induced by shock conditioning and contingency reversal

Dynamic Imaging of Deep Brain Structures with MEG: Contributions to Understanding Human Memory

Contact Info

Product

Resources

About