Lean body mass and bone mineral density in physically exercising postmenopausal women

Douchi, Tsutomu; Matsuo, Takashi; Uto, Hirofumi; Kuwahata, Tomoki; Oki, Toshimichi; Nagata, Yukihiro

doi:10.1016/s0378-5122(03)00143-9

Cited by 36 publications

(18 citation statements)

References 22 publications

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“…Intervention studies have shown that exercise is associated with higher bone density and lower fat mass (23,24). However, when we examined the ORs of %FM on bone outcomes, whether or not we took physical activity into account did not appreciably change the results.…”

Section: Discussionmentioning

confidence: 90%

Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

Hsu

Venners

Terwedow

et al. 2006

The American Journal of Clinical Nutrition

460

273

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Background: Higher fat mass may be an independent risk factor for osteoporosis and osteoporotic fractures. Objective: We aimed to determine the independent contribution of fat mass to osteoporosis and to estimate the risk of osteoporotic fractures in relation to body weight, lean mass, and other confounders. Design: This was a community-based, cross-sectional study of 7137 men, 4585 premenopausal women, and 2248 postmenopausal women aged 25-64 y. Total-body and hip bone mineral content (BMC) and bone mineral density (BMD) and body composition were measured by dual-energy X-ray absorptiometry. Serum lipids were measured. Sex-and menopause-specific multiple generalized linear models were applied. Results: Across 5-kg strata of body weight, fat mass was significantly inversely associated with BMC in the whole body and total hip. When we compared the highest quartile with the lowest quartile of percentage fat mass in men, premenopausal women, and postmenopausal women, the adjusted odds ratios (95% CIs) of osteoporosis defined by hip BMD were 5.2 (2.1, 13.2), 5.0 (1.7, 15.1), and 6.9 (4.3, 11.2), respectively. Significant linear trends existed for higher risks of osteoporosis, osteopenia, and nonspine fractures with higher percentage fat mass. Significant negative relations were found between whole-body BMC and cholesterol, triacylglycerol, LDL, and the ratio of HDL to LDL in all groups. Conclusions: Risks of osteoporosis, osteopenia, and nonspine fractures were significantly higher for subjects with higher percentage body fat independent of body weight, physical activity, and age. Thus, fat mass has a negative effect on bone mass in contrast with the positive effect of weight-bearing itself.Am J Clin Nutr 2006; 83:146 -54.

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Section: Discussionmentioning

confidence: 90%

Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

Hsu

Venners

Terwedow

et al. 2006

The American Journal of Clinical Nutrition

460

273

View full text Add to dashboard Cite

show abstract

“…6,40 However, according to Douchi et al, 7 lean mass is a more significant determinant of BMD for exercising postmenopausal women compared with sedentary women. 7 In that case, physical training composed of dynamic and resistance exercises 41 is important to prevent disability in aging and can also help to preserve muscle mass and force.…”

Section: Discussionmentioning

confidence: 99%

Effects of excess body mass on strength and fatigability of quadriceps in postmenopausal women

et al. 2012

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“…Studies in men, and preand post-menopausal women have reported that lean mass is a key determinant of BMD [3][4][5], whereas some studies of postmenopausal women have suggested that fat mass plays a key role [6,7], and both lean and fat mass have been reported to be significant predictors of BMD in other studies of men and pre-and post-menopausal women [8][9][10]. This heterogeneity in findings could arise from differences between studies in age, gender and ethnicity of participants (with associated differences in body composition), in turn reflecting the different mechanisms by which lean and fat mass influence bone mass.…”

Section: Introductionmentioning

confidence: 99%

Associations between body mass index, lean and fat body mass and bone mineral density in middle-aged Australians: The Busselton Healthy Ageing Study

Zhu¹,

Hunter²,

James³

et al. 2015

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Lean body mass and bone mineral density in physically exercising postmenopausal women

Cited by 36 publications

References 22 publications

Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

Effects of excess body mass on strength and fatigability of quadriceps in postmenopausal women

Associations between body mass index, lean and fat body mass and bone mineral density in middle-aged Australians: The Busselton Healthy Ageing Study

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