Leakage from Retinal Capillaries in Hereditary Dystrophies

Notting, J. G. A.; Deutman, August F.

doi:10.1007/978-94-010-1573-8_65

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1978

1987

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Cited by 8 publications

(4 citation statements)

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“…However, the highly vascular nature of the arcuate area may account for the commonly observed leakage at this site. In some patients dilatation of the retinal capillaries was observed without dye leakage; this abnormality has been observed in other receptor dystrophies (Notting and Deutman, 1976).…”

Section: Discussionmentioning

confidence: 56%

Retinitis pigmentosa and retinal oedema.

Spalton¹,

Bird²,

Cleary³

1978

British Journal of Ophthalmology

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Section: Discussionmentioning

confidence: 56%

Retinitis pigmentosa and retinal oedema.

Spalton¹,

Bird²,

Cleary³

1978

British Journal of Ophthalmology

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“…4) is not too surprising since retinal vascular abnormalities are rather frequently seen in hereditary dystrophies of the retina (3,4,14).…”

Section: Discussionmentioning

confidence: 99%

Gyrate atrophy of the choroid and retina with reticular pigmentary dystrophy and ornithine-ketoacid-transaminase deficiency

1978

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A 10 year old white girl is presented with gyrate atrophy of the choroid and retina (atrofia gyrata). She also showed reticular pigmentations at the level of the retinal pigment epithelium temporal to both maculas. A generalized hyperornithinaemia was demonstrated in this patient and cultured fibroblasts established the underlying ornithine-keto-acid-transaminase (OKT) deficiency for the first time. Pharmacologic doses of vitamin B6 nor restriction of dietary protein resulted in a significant decrease of the serum ornithine concentration. It is probable that hyperornithinaemia in itself is not the cause of the gyrate atrophy.

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“…Notting and Deutman (1976) reported capillary leakage from inframacular capillaries in the posterior pole of 1 patient with a progressive cone dystrophy. That Fig.…”

Section: Discussionmentioning

confidence: 98%