2019
DOI: 10.1016/j.toxrep.2019.08.001
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Abstract: Lead (Pb) is an environmental neurotoxicant, and has been implicated in several neurological disorders of dopaminergic dysfunction; however, the molecular mechanism of its toxicity has yet to be fully understood. This study investigated the effect of Pb exposure on dopaminergic neurodegeneration and function, as well as expression level of several dopaminergic signaling genes in wild type (N2) and protein kinase C ( pkc ) mutant Caenorhabditis elegans . Both N2 and…

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