Leaching behavior of veterinary antibiotics in animal manure-applied soils

Pan, Min; Chu, L.M.

doi:10.1016/j.scitotenv.2016.11.072

Cited by 103 publications

(50 citation statements)

References 43 publications

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“…Increasingly alkaline soil pH may also contribute to TC leaching since the predominantly anionic species will not sorb as strongly to soils. In column studies investigating the effect of acid rain on TC mobility in soil following surface application of TC-spiked chicken manure (2000 g TC kg soil −1 ), TC was found in the top 20 cm at a concentration of 17.1 g kg −1 after pH 3 rain, but was found at 0-40 cm depth at 6.57 g kg −1 after pH 7 rain, demonstrating its mobility in soil at higher pH (Pan and Chu 2017). In an extensive survey of three dairy farms in China, Zhou et al (2013) analyzed the concentrations of 50 antibiotics in the fecal waste and wastewater.…”

Section: Tc Transport Through Soilsmentioning

confidence: 99%

“…Moreover, because antibiotics are given for prophylactic, metaphylactic, and growth-promoting purposes, the antibiotic load present in manure far surpasses historic quantities when more conservative practices were employed. Through land-application of antibiotic-rich animal waste in concentrated geographical regions, the soil serves as a repository for pharmaceuticals from which TCs may leach into groundwater, enter surface waters via overland flow, or persist in soil (Kwon 2011;Zhou et al 2013;Pan and Chu 2017).…”

Section: Introductionmentioning

confidence: 99%

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Fate of tetracycline antibiotics in dairy manure-amended soils

Pollard

Morra

2018

Environ. Rev.

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The US dairy industry has changed significantly during the past 20 years. The number of dairies declined 63% from 1997 to 2012 owing to the rise in concentrated animal feeding operations and the concomitant decline of small dairy farms. Efficient and cost-effective dairies adhering to the concentrated animal feeding operation business design are praised for their high milk production. However, with a per capita daily manure production of 55 kg, storage and disposal of manure at these large operations pose significant management challenges and environmental risks. Application to surrounding agricultural fields is a common practice for disposing of manure, but the fate and consequences of antibiotics present in dairy waste are issues of great concern. Although antibiotics in the environment promote microbial resistance, their risks to humans and the environment are not completely known. Understanding and predicting the fate of antibiotics from dairy manure in soils is complicated by the variability and complex interactions of soil factors in addition to the diversity of chemicals of emerging concern, their amphoteric structures, and potential antagonistic and synergistic interactions among chemicals of emerging concern. This review explores behavior of the tetracycline (TC) class of antibiotics from dairy manure in the soil environment. TC fate in soils depends significantly on soil pH, ionic strength, and soil organic matter (SOM). Molecular charge and physicochemical properties of TCs at typical soil pHs encourage strong sorption to soils; however, this interaction is complicated by organic matter and metals, and may also encourage development of antibiotic resistance. Furthermore, TC degradation products exhibit distinct properties from their parent compounds that also must be considered. Increased knowledge of the behavior of TC antibiotics in soil is needed to enable mitigation of their potential risks.

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Section: Tc Transport Through Soilsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fate of tetracycline antibiotics in dairy manure-amended soils

Pollard

Morra

2018

Environ. Rev.

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“…Antibiotics belong to a group of pharmaceuticals that have recently been excessively used, consequently leading to their accumulation in various parts of the environment, including the soil. Studies have shown that the concentration of antibiotics in the soil can range from a few nanograms to even 50 mg/kg of soil [1][2][3][4]. Antibiotics, as organic compounds, can be subjected to various processes in the soil environment, the most important of which are sorption on soil components, as well as transformation and/or degradation [5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Functional Diversity of Soil Microbial Communities in Response to the Application of Cefuroxime and/or Antibiotic-Resistant Pseudomonas putida Strain MC1

et al. 2018

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Cefuroxime (XM), the most commonly prescribed antibiotic from the cephalosporin group, may cause changes in the structure of the soil microbial community, and these changes may also be reflected in the alteration of its functionality. Therefore, due to the lack of studies on this topic, the scope of this study was to assess the functional diversity and catabolic activity of the microbial community in soil treated with XM (1 mg/kg and 10 mg/kg soil) using the community-level physiological profile (CLPP) approach during a 90-day experiment. In addition, the effect of antibiotic-resistant Pseudomonas putida strain MC1 (Ps) was also evaluated. The resistance/resilience concept and multifactorial analysis were used to interpret the data. The results showed that the introduction of XM and/or Ps into the soil caused changes in the catabolic activity and functional diversity of the microbial community. A decrease in the values of the CLPP indices (i.e., microbial activity expressed as the average well-color development (AWCD), substrate richness (R), the Shannon-Wiener (H) and evenness (E) indices and the AWCD values for the six carbon substrate groups) for the XM-treated soil was generally detected up to 30 days. In turn, at the same time, the activity measured in the Ps-inoculated soil was higher compared to the control soil. A stimulatory effect of XM at 10 mg/kg (XM10) and XM10+Ps on the utilization pattern of each substrate group was found at the following sampling times (days 60 and 90). The AWCD values for the utilization of amines, amino acids, carbohydrates, carboxylic acids, miscellaneous compounds and polymers for these treatments were found to be up to 2.3-, 3.1-, 2.3-, 13-, 3.4- and 3.3-fold higher compared to the values for the nontreated control, respectively. The resistance of the CLPP indices and the AWCD values for the carbon substrate groups were categorized as follows: E > H > R > AWCD and amino acids = carbohydrates > polymers > amines > miscellaneous > carboxylic acids, respectively. The results suggest a low initial resistance of the soil microbial community to XM and/or Ps, and despite the short-term negative effect, the balance of the soil ecosystem may be disturbed.

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“…Controlled laboratory experiments offer an alternative, more comprehensive method to collect and analyze fate and transport data of CECs; however, data extrapolation to field predictions is limited by artifacts associated with column configuration (Kay et al, 2005a; Blackwell et al, 2009). Specifically, most soil column studies use packed soil columns that are relatively short (10–50 cm), impose saturated conditions, and collect data for a relatively limited time (Boll et al, 1992; Chen et al, 2013; Pan and Chu, 2017). …”

mentioning

confidence: 99%

Transport of Potential Manure Hormone and Pharmaceutical Contaminants through Intact Soil Columns

et al. 2019

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Although adding manure to agricultural soils is a commonly practiced disposal method and a means to enhance soil productivity, potential environmental contamination by any associated chemicals of emerging concern (CECs) such as hormones and pharmaceuticals is not well understood. Our objective was to provide field‐relevant predictions of soil transport and attenuation of 19 potential manure CECs using undisturbed soil columns irrigated under unsaturated conditions. The CEC concentrations in leached water were monitored for 13 wk using high performance liquid chromatography–time of flight–mass spectrometry (HPLC‐TOF‐MS), after which time soil in the cores was removed and sampled for extractable CECs. Compounds quantified in column leachate included all four of the added sulfonamide antibiotics and the nonsteroidal, anti‐inflammatory drug flunixin. Only trace amounts of several of the seven hormones, five remaining antibiotics, and two antimicrobials leached from the columns from exogenous soil additions. Soil residues of all 19 compounds were detected, with highest extractable amounts for 17α‐hydroxyprogesterone > triclosan (antimicrobial) > flunixin > oxytetracycline. Those CECs with the highest recoveries as calculated by summing leached and extractable amounts were flunixin (14.5%), 17α‐hydroxyprogesterone (5.3%), triclosan (4.6%), and sulfadimethoxine (4.8%). Manure management to prevent CEC contamination should consider the potential environmental problems caused by negatively charged compounds with the greatest mobility (flunixin and sulfadimethoxine) and those that have long residence times in soil (triclosan, 17α‐hydroxyprogesterone, flunixin, and oxytetracycline). Flunixin is particularly important given its mobility and long residence time in soil. Core Ideas Four sulfonamide antibiotics and the drug flunixin leached through soil columns. Trace amounts of nonsulfonamide antibiotics were detected in column leachate. Soil extracts contained 17α‐hydroxyprogesterone > triclosan > flunixin > oxytetracycline. The highest recoveries were observed for flunixin and 17α‐hydroxyprogesterone.

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Leaching behavior of veterinary antibiotics in animal manure-applied soils

Cited by 103 publications

References 43 publications

Fate of tetracycline antibiotics in dairy manure-amended soils

Fate of tetracycline antibiotics in dairy manure-amended soils

Functional Diversity of Soil Microbial Communities in Response to the Application of Cefuroxime and/or Antibiotic-Resistant Pseudomonas putida Strain MC1

Transport of Potential Manure Hormone and Pharmaceutical Contaminants through Intact Soil Columns

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