Road Traffic Accident (RTA) are a major health problem in Morocco. Those involving rear cargo tricycles for passenger transport or mixed transport use require special attention. An 18-month continuous retrospective study was performed. It included all victims of RTA involving at least one tricycle, admitted to emergency department with a documented traumatic injury. The data collected was analyzed by statistical software (SPSS v18.0). The aim of this study was to assess the epidemiological, lesional and therapeutic characteristics of stroke’s victims involving tricycles in the region of Grand Casablanca in Morocco. It also highlights the frequency and severity of injuries related to motorized tricycles accidents and the interest of regulatory enforcement to reduce the incidence of these accidents.