Le carcinome mucoépidermoïde du poumon

Mezni, Faouzi El; Salha, Illé; Ismail, O.; Braham, Emna; Zeddini, A.; Ayadi-Kaddour, A.; Bousnina, S.; Kilani, T.

doi:10.1016/s0761-8417(05)84793-5

Cited by 7 publications

(2 citation statements)

References 9 publications

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“…Two of these patients had high-grade MEC and one had a low-grade lesion. The remaining seven patients were alive without evidence of recurrence [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…Histopathological findings were diagnostic of a low-grade MEC with a confirmed complete tumor resection with negative surgical margins and no evidence of metastatic spread to lymph nodes. Based on the experience of multiple groups in treating low-grade MEC [ 4 , 7 , 9 – 11 , 13 ], surgical treatment is curative in this group of patients. No studies support the use of adjuvant chemotherapy, targeted therapy, or radiation therapy for low-grade pulmonary MECs given the excellent survival rates achieved with surgery alone.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Mucoepidermoid Carcinoma of the Lung: A Case Report and Literature Review

Alsidawi

Morris

Wikenheiser-Brokamp

et al. 2013

Case Reports in Oncological Medicine

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Introduction. Mucoepidermoid carcinoma (MEC) of the lung is a rare form of lung cancer that is classified into low grade and high grade based on histological features. Surgical resection is the primary treatment for low-grade MEC with excellent outcomes, while high-grade MEC is a more aggressive form of malignancy. Clinical Case. We report a case of a 46-year-old woman who presented with dyspnea on exertion. Imaging studies revealed a mass involving the right upper lobe bronchus. Bronchoscopy, surgical resection, and pathological examination revealed a low-grade MEC with tumor-free margins. No adjuvant treatment was given. Discussion. Primary pulmonary MEC is a rare type of lung cancer with only few reported cases. This patient illustrates a typical presentation for low-grade MEC wherein surgical resection is considered curative. In contrast, high-grade MEC is a more aggressive malignancy with a poorer outcome. The role of targeted therapy directed against EGFR or a novel CRTC1-MAML2 fusion protein expressed in some high-grade tumors is yet to be determined.

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“…Two of these patients had high-grade MEC and one had a low-grade lesion. The remaining seven patients were alive without evidence of recurrence [ 11 ].…”

Section: Discussionmentioning

confidence: 99%