Le cannabis : similitudes et différences avec le tabac

Place of therapeutic cannabis in France and safety data: A literature review

“…However, there is conflicting evidence of an association between cannabis use and the development of chronic obstructive pulmonary disease (58,59). It should be noted that the changes in respiratory functions associated with chronically smoked cannabis are difficult to dissociate from those caused by tobacco alone because of consumption habits that include tobacco (60).…”

Tobacco and cannabis co-use : toxicity, dependence and cessation management.

“…As most studies express cumulative tobacco consumption in pack-years (1 pack-year [PA] corresponds to 1 pack of cigarettes smoked per day for 1 year), cannabis consumption is expressed in 28 joint-years (1 joint-year [JA] corresponds to 1 joint smoked per day for 1 year). These methods of calculation are approximate, particularly for cannabis, as the quantity of substance used to make a joint and the depth of each puff inhaled are highly variable [3].…”

“…Apart from nicotine and cannabinoids, which are specific to tobacco and cannabis, the smoke produced by combustion of both contains the same toxic substances (carbon dioxide, acrolein, benzene, toluene) and carcinogens (vinyl chloride, dimethylnitrosamine, methyl ethylnitrosamine, benzopyrene, benzanthracene) [3][4][5]. A study [9] has shown that cannabis smoke contained ammonia in concentrations 20 times higher than tobacco smoke, and hydrogen cyanide and nitric oxide concentrations 3 to 5 times higher.…”

“…Mortality due to its use is unknown, but it is the cause of many morbid effects ; many users believe that smoking cannabis carries little health risk. Cannabis use often is associated with tobacco use, making it more difficult to stop [3,4]. The objective of this article is to review the data on Tobacco and cannabis co-use regarding toxicity, dependence as well as management of cessation…”

Composição do cigarro de tabaco e Cannabis e suas possíveis ações na gênese do câncer de pulmão

“…A composição química da fumaça do tabaco foi amplamente investigada, entretanto, comparativamente, existem poucos relatos da composição química da fumaça da maconha (Graves et al, 2020). Contudo, nestes trabalhos, produtos químicos como óxidos de nitrogênio, cianeto de hidrogênio e aminas aromáticas foram encontrados na fumaça da maconha em concentrações três a cinco vezes maiores que na fumaça do tabaco (Moir et al, 2008;Mura et al, 2020). O material particulado total e o alcatrão, comumente associados à fumaça do tabaco, também são encontrados em concentrações semelhantes ou superiores na fumaça da maconha (Wu et al 1988;Moir et al 2008).…”