LC–MS/MS for the simultaneous analysis of arachidonic acid and 32 related metabolites in human plasma: Basal plasma concentrations and aspirin-induced changes of eicosanoids

A quantitiative LC-MS/MS method for the measurement of arachidonic acid, prostanoids, endocannabinoids, N-acylethanolamines and steroids in human plasma

“…Consequently, we selected ACN precipitation, followed by SPE clean up, could not be analyzed in this mode [24,[36][37][38]. Only one publication measured AA in positive mode (using a Micromass Quatro Micro spectrometer from Waters) [39], but these results could not be reproduced using our instrument.…”

“…It has been widely used for the analysis of ECs and similar lipids [24][25][26][27][28]. However, it has only recently been used for the analysis of steroids [29][30][31].…”

Effect of Cigarette Smoking on the Production of 20-Hydroxyeicosatetraenoic Acid in Human Platelet

“…Then, the residues were reconstituted in ethanol for analysis using liquid chromatography-mass spectrometry system (LC/MS) (Applied Biosystems, Foster City, CA); as published previously. 10 …”

Pharmaceutical electrochemistry: The electrochemical detection of aspirin utilising screen printed graphene electrodes as sensors platforms

“…In 1763 the active ingredient of Aspirin was discovered by Edward Stone from the bark of the willow. A number of analytical approaches have been employed to analyse ASA such as: highperformance liquid chromatography-mass spectrometry [2][3][4][5][6] and gas chromatography-mass spectrometry [7], ultra performance liquid chromatography tandem mass spectrometry [8] and capillary electrophoresis [9] have also been reported for the determinations of ASA. However, many of these methods require sample pre-treatment, several timeconsuming manipulation steps, sophisticated instruments and special training.…”