LC–MS-Based Direct Quantification of MicroRNAs in Rat Blood
Hyun-Deok Cho,
Jung Eun Min,
Myeongjin Choi
et al.
Abstract:MicroRNA (miRNA) has recently garnered significant research attention, owing to its potential as a diagnostic biomarker and therapeutic target. Liquid chromatography−mass spectrometry (LC−MS) offers accurate quantification, multiplexing capacity, and high compatibility with various matrices. These advantages establish it as a preferred technique for detecting miRNA in biological samples. In this study, we presented an LC− MS method for directly quantifying seven miRNAs (rno-miR-150, 146a, 21, 155, 223, 181a,… Show more
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