LC-ESI/LTQOrbitrap/MS/MS and GC–MS profiling of Stachys parviflora L. and evaluation of its biological activities

Shakeri, Abolfazl; D’Urso, Gilda; Taghizadeh, Seyedeh Faezeh; Piacente, Sonia; Norouzi, Saeed; Soheili, Vahid; Asili, Javad; Salarbashi, Davoud

doi:10.1016/j.jpba.2019.02.018

Cited by 33 publications

(25 citation statements)

References 30 publications

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“…vacillans ) were investigated in different works [ 81 , 108 , 112 ]. The antioxidant capacity of the methanol extract of S. parviflora was measured, exhibiting an IC 50 value of 76.87 ± 0.57 μg/mL (DPPH method) and of 188.47 ± 0.76 μg/mL (β-carotene bleaching test; BCB), while the standard compound, butylated hydroxytoluene (BHT), had stronger activity in both tests (DPPH test: IC 50 = 1.23 ± 0.02 μg/mL; BCB test: 34.31 ± 0.40 μg/mL) [ 64 ]. Guo et al (2018) examined the antioxidant activity of five fractions from the 70% ethanol extract of tubers of S. affinis by DPPH assay and superoxide radical scavenging activity [ 28 ].…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

“…japonica on UVA-irradiated HDFs was evaluated at different concentrations for 48 h by MTT assay, showing no or little cytotoxicity [ 160 ]. Shakeri et al (2019) mentioned that the methanol extract of S. parviflora demonstrated no cytotoxic activity toward the cancer cell lines, namely A2780, HCT, and B16F10 in all tested concentrations (>100 µg/mL) [ 64 ]. Moreover, the genotoxic activity of the extracts from four different plants were investigated by Slapšytė and colleagues (2019) [ 157 ].…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

“…The ethyl acetate extract demonstrated the best inhibition against Escherichia coli (MIC = 64 ± 0.60 μg/mL), whereas it didn′t show any activity against P. aeruginosa and M. morganii . Shakeri et al (2019) reported the antimicrobial activity of the methanol extract of the aerial parts of S. parviflora which exerted the highest activity against the Gram-positive bacterium, Bacillus cereus , with a MIC of 0.12 mg/mL [ 64 ]. Furthermore, the antimicrobial activity of extracts of S. thirkei against different microorganisms were studied according to inhibition zone diameter and MIC value [ 84 ].…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

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Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

2020

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Section: Pharmacological Activitiesmentioning

confidence: 99%

Section: Pharmacological Activitiesmentioning

confidence: 99%

Section: Pharmacological Activitiesmentioning

confidence: 99%

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Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

2020

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“…Piper aleyreanum -DPPH [61] Psidium guineense -DPPH, ABTS [238] Pomelo peel -DPPH, ABTS [68] Satureja hortensis -DPPH [77] Stachys cretica -DPPH [79] Stachys hydrophila -DPPH [79] Stachys palustri -DPPH [79] Stachys parviflora -DPPH, β-carotene/linoleic acid [80] Tanacetum macrophyllum -DPPH, ABTS, FRAP [83] Thymus munbyanus -DPPH, ABTS, FRAP [85] Thymus vulgaris -DPPH [125] Vetiveria zizanioides β-carotene/linoleic acid, B16 [87] Vitex Negundo -DPPH, ABTS, metal-ion chelation [88] Wedelia chinensis -B16-F10 (C57BL/6) [90,239] Eugenol A2058, SK-MEL 28 [134] where not indicated, EO active components were not available from the cited articles. When referred to in vivo studies, the murine strain used is indicated in brackets.…”

Section: Plant Name From Which Eos Were Extracted Eo Active Componentmentioning

confidence: 99%

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma

Martile

Garzoli

Ragno

et al. 2020

Cancers

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The last two decades have seen the development of effective therapies, which have saved the lives of a large number of melanoma patients. However, therapeutic options are still limited for patients without BRAF mutations or in relapse from current treatments, and severe side effects often occur during therapy. Thus, additional insights to improve treatment efficacy with the aim to decrease the likelihood of chemoresistance, as well as reducing side effects of current therapies, are required. Natural products offer great opportunities for the discovery of antineoplastic drugs, and still represent a useful source of novel molecules. Among them, essential oils, representing the volatile fraction of aromatic plants, are always being actively investigated by several research groups and show promising biological activities for their use as complementary or alternative medicine for several diseases, including cancer. In this review, we focused on studies reporting the mechanism through which essential oils exert antitumor action in preclinical wild type or mutant BRAF melanoma models. We also discussed the latest use of essential oils in improving cancer patients’ quality of life. As evidenced by the many studies listed in this review, through their effect on apoptosis and tumor progression-associated properties, essential oils can therefore be considered as potential natural pharmaceutical resources for cancer management.

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“…minimum fungicidal concentration (MFC)] were determined. In this experiment, the negative and positive controls were treated with SDB and nystatin, respectively [22].…”

Section: Minimum Inhibitory Concentration and Minimum Bactericidal Anmentioning

confidence: 99%

Assessment of in vitro bioactivities of Pis v 1 (2S albumin) and Pis v 2.0101 (11S globulin) proteins derived from pistachio (Pistacia vera L.)

et al. 2019

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We studied the biological activity of Pis v 1 (2S albumin) and Pis v 2.0101 (11S globulin) against Coxsackie viruses (CV) B2, B3, B4 and B5 as well as their cytotoxicity against six cell lines. Results showed that the two allergens of pistachio significantly reduce the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) against four Gram-positive and four Gram-negative bacteria as well as two fungi. Moreover, they exerted significant in vitro cytotoxic activities against Human ovarian carcinoma (A2780), human colon carcinoma (HTC), human glioblastoma (U-87-MG), human breast adenocarcinoma (MCF-7), and human prostate cell lines (PC3 and DU-145). Our findings revealed that the highest antimicrobial effect of the allergens was found against M. loteus (MIC = 10 µg/mL). The lowest IC 50 value was found for Pis v 2.0101 allergen (11S globulin) against CV-B4 (30.20 ± 1.01 µg/mL). Furthermore, in vitro cytotoxicity assay showed IC 50 values ranging from 21.09 ± 0.55 to 34.52 ± 0.90 and 26.34 ± 0.88 to 38.63 ± 0.80 µg/mL for Pis v 2.0101 (11S globulin) and Pis v 1 (2S albumin), respectively. As these allergens presented considerable effects against biofilm-related infections, CV-B2-5, and several cell lines, they might be employed as alternative/complementary treatments after further preclinical and clinical studies.Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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LC-ESI/LTQOrbitrap/MS/MS and GC–MS profiling of Stachys parviflora L. and evaluation of its biological activities

Cited by 33 publications

References 30 publications

Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma

Assessment of in vitro bioactivities of Pis v 1 (2S albumin) and Pis v 2.0101 (11S globulin) proteins derived from pistachio (Pistacia vera L.)

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