LB1042 Neuroimmune mediators of pruritus in scalp psoriatic itch: An immunofluorescent analysis in a Hispanic population

Nattkemper, Leigh; Lipman, Zoe M.; Ingrasci, Giuseppe; Maldonado, Claudia Gabriela Jara; Garcés, Juan Carlos; Hawash, Ahmed; Loayza, Enrique; Yosipovitch, Gil

doi:10.1016/j.jid.2022.05.1080

Cited by 1 publication

(1 citation statement)

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“…They proposed that the activation of transient receptor potential (TRP) vanilloid 1 channels facilitates communication between sensory nerve endings and immune cells in the skin, leading to an enhanced release of in ammatory mediators such as cytokines and neuropeptides [18]. Yosipovitch G studied the neuroimmune mediators of pruritus in hispanic scalp psoriatic [19]. The aforementioned studies primarily focus on the pathogenesis and therapeutic approaches pertaining to neuroimmune involvement in psoriasis.…”

Section: General Informationmentioning

confidence: 99%

Knowledge mapping of the relationship between neuroimmune and psoriasis： A Bibliometric analysis（2004-2023）

wei,

Zhang,

Wang

et al. 2023

Preprint

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Background Many studies have revealed that neuroimmune is closely related to psoriasis. However, information in this field remains ambiguous. Objective Therefore, this study aimed to examine the relationship between neuroimmune and psoriasis, identify journal publications and collaborators, and analyze keywords and research trends using a bibliometric method. Methods We systematically searched the Web of Science Core Collection (WOSCC) for papers published on neuroimmune and psoriasis. Retrieved data regarding countries, institutions, authors, journals, keywords, and so on. VOSviewer, CiteSpace, R package “bibliometrix”, and MapChart were used to visualize the information through collaborative networks. Results 398 articles from 48 countries led by the United States were included. The number of publications related to neuroimmune in psoriasis showes significantly increase in recent years. University of Miami, University of California Davis and Capital Medical University are the main research institutions. The Journal of Investigative Dermatology is the most popular journal in this field. These publications come from 2028 authors, among whom Yosipovitch G, Raychaudhuri SP and Reich A had published the most papers. High-frequency keywords included “psoriasis”, “neuroinflammation “, “atopic-dermatitis”, “nerve growth-factor”, and “expression”. Recent studies have focused on “cutaneous nervous system”, “botulinum toxin”, “dementia”, and “parkinson’s disease” according to the cocitation analysis of kewords. “Botulinum toxin”, “dementia”, “Alzheimers disease” represent the frontiers of research in this field, undergoing an explosive phase. Conclusion These findings offer valuable insights for researchers to further investigate the involvement of neuroimmune mechanisms in psoriasis.

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Section: General Informationmentioning

confidence: 99%