Layout and Post-Processing of Transcriptional Modules

Abstract

Visualization of transcriptional modules together with their transcriptional program is a non-trivial task. We have therefore developed a module visualization tool that allows visualizing overlapping transcriptional modules in a very intuitive way. By visualizing not only the genes and the experiments in which the genes are co-expressed, but also additional properties of the modules such as the regulators and regulatory motifs that are responsible for the observed coexpression, our tool can assist in the biological analysis and interpretation of the output of module detection tools.