To fabricate metallic 316L/HA (hydroxyapatite) materials which meet the requirements of an implant's mechanical properties and bioactivity for its function as human bone replacement, selective laser melting (SLM) has been employed in this study to prepare a 316L stainless steel matrix, which was subsequently covered with a hydroxyapatite (HA) coating using the sol-gel method. High density (98.9%) as-printed parts were prepared using a laser power of 230 W and a scanning speed of 800 mm/s. Austenite and residual acicular ferrite existed in the microstructure of the as-printed 316L stainless steel, and the sub-grain was uniform, whose primary dendrite spacing was around 0.35 µm. The as-printed 316L stainless steel showed the highest Vickers hardness, elastic modulus, and tensile strength at~(~means about; same applies below unless stated otherwise) 247 HV,~214.2 GPa, and~730 MPa, respectively. The elongation corresponding to the highest tensile strength was~38.8%. The 316L/HA structure, measured by the Relative Growth Rate (RGR) value, exhibited no cell cytotoxicity, and presented better biocompatibility than the uncoated as-printed and as-cast 316L samples.implants to replace shoulders, knees, and other body parts of the human being [7-9]. However, it is difficult to induce good attachment and growth of bone cells from 316L stainless steel and it also has no bioactive capabilities, which increases the likelihood for it to lead to loosening of the implant and premature failure [10][11][12]. The HA coating, however, is likely to provide excellent bioactivity and biocompatibility to metallic implants [13][14][15].For individual patients, mass-produced implants may not completely fulfill their needs. Customized implants, with geometry deriving from their own magnetic resonance imaging (MRI) data, are urgently needed [16]. SLM, which is a powder-bed-based additive manufacturing technology, can be used to selectively melt metal powders layer by layer through a highly focused and computer-controlled laser beam [17,18]. It has been used to successfully prepare many kinds of metallic biomaterials, such as stainless steel, alloys of titanium, magnesium, and medical noble metals, and compared with some of the more traditional approaches, it provides superior mechanical properties and a relatively simpler manufacturing process [19,20].In retrospect, some studies around SLM-processed 316L stainless steel with different laser parameters and lattice structure designs have been undertaken [21][22][23]. In order to testify its feasibility as an implant, simple cytotoxicity and biocompatibility tests were conducted while comparing different manufacturing and post-processing methods [24][25][26][27][28]. However, these can hardly solve the problem of poor bioactivity, and may even cause a failure of metallic implants. As a time-honored bio ceramic which realizes higher osteoblast activity, HA material is currently quite popular for its special applications in regenerative implants and bone void fillers [29]. Metallic implants, with ...