Laxative Effects of<i>Rosa damascene</i>Mill in Dogs

Abbaszadeh, Mohammad; Kazerani, Hamid Reza; Kamrani, Alireza

doi:10.1080/09712119.2010.9707162

Cited by 5 publications

(5 citation statements)

References 5 publications

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“…R. damascena is a dosedependent laxative in dogs, thus causing diarrhea at 90 mg/kg low doses. During the intervention, there are no side effects, its laxative effect has been successfully performed, and it can also have a therapeutic value (21). No significant adverse events were observed in our study during the use of R. damascena products except for mild nausea, mild flatulence, and mild diarrhea in limited cases that did not disturb patient ingestion.…”

Section: Discussionmentioning

confidence: 62%

“…The laxative and stimulating effect of R. damascena on the intestines in recent in vivo studies (19)(20)(21), the omission of the side effects in routine consumption (3), convenient access and maintenance of this herb, and popular acceptance are important reasons behind the selection of R. damascena products. This research is important as, to the best of our knowledge, it is the first clinical trial to determine the impact of R. damascena products on constipation during pregnancy.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the Effect of Rosa damascena Mill. Product on Constipation During Pregnancy: A Single-Arm Clinical Trial

Emaratkar¹,

Nili²,

Hadavand³

et al. 2020

International Journal of Women’s Health and Reproduction Scienc

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Objectives: Constipation is one of the most common issues at the time of pregnancy. Traditional Persian medicine (TPM) has always emphasized the use of safe laxatives to relieve constipation during pregnancy.The present study aimed to investigate the effect of Rosa damascena Mill. products on constipation and the quality of life during pregnancy. Materials and Methods: This is a single-arm clinical trial study on 35 pregnant women (14-34 weeks) with constipation diagnosed on the basis of Rome IV criteria in Tehran and Qom, Iran during 2018-2019. The consumption of R. damascena products was recommended daily for 4 weeks. Then, the severity of constipation and the quality of life were assessed via the Rome IV criteria and the World Health Organization (WHO) quality of life questionnaires (WHOQOL-BREF), respectively. Results: This study was performed on 35 pregnant women (14-34 weeks). The consumption of R. damascena products decreased the score of Rome IV criteria (Mean9.4 to 1.1) while increasing the frequency of bowel movements and improving the overall quality of life (P < 0.001). The predominant constipation signs, including straining, lumpy and hard stools, a sensation of incomplete evacuation, a sensation of anorectal obstruction, manual facilitation maneuvers, and less than 3 spontaneous bowel movements per week significantly improved after the consumption of R. damascena products (P < 0.001). Conclusions: Rosa damascena products can effectively treat constipation and enhance the quality of life.

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Section: Discussionmentioning

confidence: 62%

Section: Introductionmentioning

confidence: 99%

Evaluation of the Effect of Rosa damascena Mill. Product on Constipation During Pregnancy: A Single-Arm Clinical Trial

Emaratkar¹,

Nili²,

Hadavand³

et al. 2020

International Journal of Women’s Health and Reproduction Scienc

View full text Add to dashboard Cite

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“…Abbaszadeh et al also reported that the use of Rosa damascene Mill. hydroalcoholic extract in a dose-dependent manner caused diarrhea in dogs [26] . In the present study, in some participants, the frequency increased to 3 to 4 times.…”

Section: Discussionmentioning

confidence: 95%

“…It was then placed in the freezer and prepared in the required dose when used in capsules [22][23][24] ; The dose of Rosa damascene Mill. extract was selected based on the conversion of animal dose to human dose, as in a study in which the dose of 180-190mg/kg caused laxative effects in dogs, and therefore this dose was converted to human dose [25,26] . Lactulose syrup (Sobhan Company; Iran) was used as one of the standard treatments for constipation, along with Rosa damascene Mill.…”

Section: Journal Of Clinical Care and Skillsmentioning

confidence: 99%

Effect of Rosa damascene Mill. Hydroalcoholic Extract on the Treatment of Chronic Idiopathic Constipation in Adults

Mansoorkhani¹,

Alamdari²,

Hasanzadeh³

et al. 2021

J Clinic Care Skill

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Dietary fiber intake, dietary glycemic index and ... [4] Prevalence of gastrointestinal symptoms ... [5] Bowel habit reference values and ... [6] Chronic idiopathic ... [7] Constipation in children and young people ... [8] Functional chronic constipation: Rome ... [9] Essential oils and their therapeutic ... [10] The laxative and prokinetic effects of Rosa ... [11] Development and clinical evaluation of ... [12] Adverse effects ... [13] A study on the relationships between ... [14] Global value chain analysis of Damask ... [15] The effect of aromatherapy with ... [16] Induced anti-oxidation efficiency and ... [17] Interventions of Iranian traditional medicine ... [18] Ziziphus jujuba extract for the treatment ... [19] Validity and reliability of the Bristol Stool ... [20] Update on Rome IV criteria for colorectal ... [21] The constipation severity instrument ... [22] Pharmacological effects of Rosa ... [23] Analgesic and anti-inflammatory effects ... [24] Hepatoprotective effect of Stachys pilifera ... [25] A simple practice guide for dose ... [26] Laxative effects of Rosa damascene Mill ... [27] Chemical constituents, experimental and ... [28] An in vitro evaluation of various Rosa damascena ... [29] Effect of aqueous fraction of Rosa damascena ... [30] Effect of Rosa damascena Mill. flower ... [31] Comparative efficacy and safety of ... [32] Cochrane review: Lactulose versus ... [33] Polyethylene glycol 3350 without electrolytes ... [34] Lactitol or lactulose in the treatment ... [35] Relaxing effect of rose oil on ...

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“…It is also mainly used in soaps, cosmetics, toiletries and perfumes 7 . Several pharmacological effects such as antibacterial, 8 antimicrobial, 9 anticancer, 10 antidiabetic, 11 anti‐ageing, 12 laxative/purgative, 13 anti‐inflammatory properties as well as its use in aromatherapy for relaxing and the treatment of cardiac diseases were reported for Rosa damascena Mill 14…”

Section: Introductionmentioning

confidence: 99%

Evaluation of adulteration in distillate samples of Rosa damascena Mill using colorimetric sensor arrays, chemometric tools and dispersive liquid–liquid microextraction‐GC‐MS

Mahboubifar

Hemmateenejad

Jassbi

2021

Phytochemical Analysis

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Introduction Rosa damascena Mill distillate and its essential oil are widely used in cosmetics, perfumes and food industries. Therefore, the methods of detection for its authentication is an important issue. Objectives We suggest colorimetric sensor array and chemometric methods to discriminate natural Rosa distillate from synthetic adulterates. Material and methods The colour responses of 20 indicators spotted on polyvinylidene fluoride (PVDF) substrate were monitored with a flatbed scanner; then their digital representation was analysed with principal component analysis (PCA), partial least squares‐discriminant analysis (PLS‐DA) and soft independent modelling of class analogy (SIMCA). Results Accurate discrimination of the diluted‐ and synthetic‐mixture samples from the original ones was achieved by PLS‐DA and SIMCA models with error rate of 0.01 and 0, specificity of 0.98 and 1, sensitivity of 1 and 1, and accuracy of 0.98 and 0.96, respectively. Discrimination of the synthetic adulterate from the original samples was achieved with error rate of 0.03 and 0.03, specificity of 0.94 and 0.93, sensitivity of 1 and 1, and accuracy of 0.93 and 0.71 with PLS‐DA and SIMCA models, respectively. Moreover, the chemical constituents of the samples were analysed using dispersive liquid–liquid microextraction and gas chromatography‐mass spectrometry (GC‐MS). The main constituents of the distillate were geraniol, citronellol, and phenylethyl alcohol in different percentages, in both original and synthetic adulterate samples. Conclusion These results point out the successful combination of colorimetric sensor array and PLS‐DA and SIMCA as a fast, sensitive and inexpensive screening tool for discrimination of original samples of R. damascena Mill distillate from those prepared from synthetic Rosa essential oils.

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Laxative Effects ofRosa damasceneMill in Dogs

Abstract: Abbaszadeh, M., Kazerani, H.R. and Kamrani, A. 2010

Cited by 5 publications

References 5 publications

Evaluation of the Effect of Rosa damascena Mill. Product on Constipation During Pregnancy: A Single-Arm Clinical Trial

Evaluation of the Effect of Rosa damascena Mill. Product on Constipation During Pregnancy: A Single-Arm Clinical Trial

Effect of Rosa damascene Mill. Hydroalcoholic Extract on the Treatment of Chronic Idiopathic Constipation in Adults

Evaluation of adulteration in distillate samples of Rosa damascena Mill using colorimetric sensor arrays, chemometric tools and dispersive liquid–liquid microextraction‐GC‐MS

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