Laugier-Hunziker syndrome: A case report

Laugier–Hunziker Syndrome in an 8-Year-Old Boy with Scleral Melanocytosis, Lingual Pigmentation, Labial Pigmentation, and Melanonychia Striata

“…Mucosal involvement in Laugier-Hunziker syndrome is characterized by asymptomatic, gray, light brown, brown, brown-black, blue-black, or black macules on the oral and genital mucosa [1,3,6]. e macules usually have welldefined margins which may be oval, lenticular, linear, or irregular in shape and less than 5 mm in diameter [3,6,8,9]. ese macules may be solitary or multiple and sometimes confluent [9].…”

“…e macules usually have welldefined margins which may be oval, lenticular, linear, or irregular in shape and less than 5 mm in diameter [3,6,8,9]. ese macules may be solitary or multiple and sometimes confluent [9]. Oral lesions are commonly seen on the labial mucosa (particularly the lower lip) and buccal mucosa [6,8,9].…”

“…ese macules may be solitary or multiple and sometimes confluent [9]. Oral lesions are commonly seen on the labial mucosa (particularly the lower lip) and buccal mucosa [6,8,9]. Less frequently, the lesions are present on the gingiva, palate, floor of the mouth, and tongue [6,8,9].…”

“…Oral lesions are commonly seen on the labial mucosa (particularly the lower lip) and buccal mucosa [6,8,9]. Less frequently, the lesions are present on the gingiva, palate, floor of the mouth, and tongue [6,8,9]. Rarely, the lesions are on the conjunctiva [10][11][12].…”

“…In the mean time, we suggest ocular pigmentation be grouped under the umbrella "essential melanotic pigmentation of mucosa." Melanonychia striata is present in approximately 50 to 60% of patients with Laugier-Hunziker syndrome and may present as single, double, or multiple longitudinal stripes that runs along the longitudinal axis of the nail from the proximal nail fold to the distal nail plate or, less commonly, as homogeneous pigmentation involving one half of the nail or complete nail [3,6,9,18]. e coloration can be tan, brown, gray, or black [18].…”