Latex allergy in pediatric surgery is dependent on repeated operations in the first year of life

Prevalence of latex allergy in a population of patients diagnosed with myelomeningocele

“…16,17 It has been demonstrated that the number of surgeries, especially in the first year of life, is the most important risk factor for sensitization and it is directly related to higher levels of latexspecific IgE. 6,16 Degenhardt, et al 16 assessed 86 patients (mean age: 10.2 years old) with a history of gastrointestinal or urological surgical procedures and found that having more than eight surgeries in the first year of life significantly increased the risk of latex allergy. Studies conducted in adult patients with a condition other than myelomeningocele demonstrated that having more than 10 surgeries was significantly associated with latex allergy (p < 0.001).…”

“…18 L a t e x a l l e r g y i n p a t i e n t s w i t h m y e l o m e n i n g o c e l e a p p e a r s t o b e o f multifactorial origin, related to a sensitization tendency, exposure and number of surgeries. 19 Considering results, it is essential to perform a risk assessment in these patients, 16,18 generate "latex-safe" environments where potentially severe allergic reactions may be prevented, and also highlight that primary prevention protocols in children with myelomeningocele may reduce the frequency of latex sensitization, therefore preventing these children from being exposed to latex since birth.…”

Allergic Reactions in the Perioperative Period in Children

“…It has been observed that the risk of latex allergies is higher when 8 or more surgeries have been practiced in the first year of life of the patient [62], reaching even higher levels of risk when concerning patients with esophageal atresia or spina bifida, where two surgeries have been seen to be enough to cause sensitization towards this agent, one event for esophageal atresia and a minimum of four surgeries in those presenting a urological malformation [44].…”

Latex allergy: current state of the problem

“…У таких детей также вы сок риск сенсибилизации и аллергии к латексу, но он все же ниже, чем у детей с SB [66]. Последнее обыч но объясняют тем, что детей с такими пороками опе рируют не столь часто, как детей с SB, а также тем, что контакт латексных аллергенов с мозговыми обо лочками может иметь большее аллергизирующее действие, чем соприкосновение со слизистой брюш ной полости.…”