Latex allergy in fruit‐allergic patients

Ortiz, José; Moyano, J. C.; Álvarez, María José; Bellido, J.

doi:10.1111/j.1398-9995.1998.tb04092.x

Cited by 79 publications

(20 citation statements)

References 28 publications

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“…Specifying the actual food allergy showed that fruit and shellfish were most important. NRL proteins are reported to cross-react with a wide variety of fruits [20, 21], but the presence of common allergens in latex and shellfish has not been reported [22]. The effect of more specified food items may be of importance, but due to small numbers this could not be investigated in the present study.…”

Section: Discussioncontrasting

confidence: 47%

Self-Reported Skin and Respiratory Symptoms Related to Latex Exposure among 5,087 Hospital Employees in Norway

Holter

Irgens²,

Nyfors³

et al. 2002

Dermatology

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Background: Latex allergy has become prevalent among health care workers. Objectives: To determine the prevalence of self-reported symptoms related to latex exposure among hospital personnel. Methods: Questionnaires addressing symptoms and risk factors for latex allergy were distributed to all employees (n = 5,087) at Haukeland University Hospital. Results: Symptoms associated with latex exposure were reported by 23.8% of the participants. Skin symptoms were most frequently reported – flushing/itching/hives: 21.0%, hand eczema: 11.8% – while systemic and respiratory symptoms were reported by 1.4 and 1.2%, respectively. Approximately twice as many women than men reported symptoms (odds ratio 2.55, confidence interval 2.04–3.18). Symptoms were reported by 33.7% of those with atopy and by 20.0% of those without. The occurrence of symptoms increased significantly with the frequency of use of latex gloves but was unrelated to age, years of exposure or number of surgical procedures. Conclusions: The occurrence of self-reported symptoms was associated with the frequent use of latex gloves, atopy and female gender.

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Section: Discussioncontrasting

confidence: 47%

Self-Reported Skin and Respiratory Symptoms Related to Latex Exposure among 5,087 Hospital Employees in Norway

Holter

Irgens²,

Nyfors³

et al. 2002

Dermatology

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“…In 30–70% of patients with a latex allergy associated food allergies have been observed, particularly to banana, avocado, chestnut, kiwifruit (see kiwifruit allergy), and many more . About 11% of patients with a fruit allergy showed symptoms after latex challenge . Oropharyngeal symptoms are frequently observed, but in about 10% of latex associated food allergies anaphylactic reactions have been observed.…”

Section: Clinical Relevance Diagnosis and Managementmentioning

confidence: 99%

EAACI Molecular Allergology User's Guide

Matricardi

Kleine-Tebbe²,

Hoffmann

et al. 2016

Pediatric Allergy Immunology

729

870

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The availability of allergen molecules ('components') from several protein families has advanced our understanding of immunoglobulin E (IgE)-mediated responses and enabled 'component-resolved diagnosis' (CRD). The European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User's Guide (MAUG) provides comprehensive information on important allergens and describes the diagnostic options using CRD. Part A of the EAACI MAUG introduces allergen molecules, families, composition of extracts, databases, and diagnostic IgE, skin, and basophil tests. Singleplex and multiplex IgE assays with components improve both sensitivity for low-abundance allergens and analytical specificity; IgE to individual allergens can yield information on clinical risks and distinguish cross-reactivity from true primary sensitization. Part B discusses the clinical and molecular aspects of IgE-mediated allergies to foods (including nuts, seeds, legumes, fruits, vegetables, cereal grains, milk, egg, meat, fish, and shellfish), inhalants (pollen, mold spores, mites, and animal dander), and Hymenoptera venom. Diagnostic algorithms and short case histories provide useful information for the clinical workup of allergic individuals targeted for CRD. Part C covers protein families containing ubiquitous, highly cross-reactive panallergens from plant (lipid transfer proteins, polcalcins, PR-10, profilins) and animal sources (lipocalins, parvalbumins, serum albumins, tropomyosins) and explains their diagnostic and clinical utility. Part D lists 100 important allergen molecules. In conclusion, IgE-mediated reactions and allergic diseases, including allergic rhinoconjunctivitis, asthma, food reactions, and insect sting reactions, are discussed from a novel molecular perspective. The EAACI MAUG documents the rapid progression of molecular allergology from basic research to its integration into clinical practice, a quantum leap in the management of allergic patients.

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“…In the latter, fruit class 1 chitinases displaying hevein‐like domains have been identified as major cross‐reactive allergens [17, 26, 27]. As fig fruit hypersensitivity has been described also in the context of latex‐associated food allergy, although not very often [28–30], it is well conceivable that hevein‐like allergens in fig, similar to those identified in FB latex [16], are important allergens. However, there is sufficient evidence now from this and previous studies that latex allergy is not mandatory in Ficus ‐related allergies.…”

Section: Discussionmentioning

confidence: 99%