Latex Allergy as a Risk During Delivery

Díaz, T. Carrillo; Martínez, T Boyano; Antépara, I.; Usandizaga, J. M.; Valverde, Miguel López; Jaurequi, I.

doi:10.1097/00006254-199608000-00011

Cited by 3 publications

(3 citation statements)

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“…This study reinforces that recommendations to prevent medication error should be implemented. 30 Unlike previous studies we did not find any cases caused by latex 31,32 . One woman had syntocinon as the only recorded cause and three women had an anaesthetic cause.…”

Section: Causal Agentscontrasting

confidence: 99%

The International Network of Obstetric Survey Systems Study of Uterine Rupture: A Descriptive Multicountry Population-based Study

Vandenberghe¹,

Bloemenkamp²,

Berlage³

et al. 2019

Obstetric Anesthesia Digest

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The incidence and outcomes of anaphylaxis in pregnancy: a UK population-based descriptive study.Objective: Anaphylaxis is a potentially fatal systemic hypersensitivity reaction, characterised by life -threatening airway, breathing or circulatory problems often with skin or mucosal change. Recent policy changes recommending administration of prophylactic antibiotics prior to caesarean delivery have led to concerns about the maternal and fetal impacts of anaphylactic reactions. The aim of this study was to estimate the incidence of anaphylaxis in pregnancy and describe the management and outcomes in the UK. Methods:A population based descriptive study was completed using the UK Obstetric Surveillance System (UKOSS) between 1 st October 2012 and 30 th September 2015. Cases of anaphylaxis were defined as a severe, life-threatening generalised or systemic hypersensitivity reaction. Results:There were 37 confirmed cases of anaphylaxis in pregnancy, giving an estimated incidence of 1.6 (95%CI 1.1-2.2) per 100,000 maternities. In cases with a single agent recorded, the main causal agents were as follows: penicillin based antibiotics (n=9), cephalosporins (n=1), imidazole (n=1), oxytocin (n=1), anaesthetic agents (n=3), blood products (n=3) and intravenous iron (n=2). There were four cases of anaphylaxis in women with known penicillin allergies: two had received co-amoxiclav and two cephalosporins. Twelve women had anaphylaxis following prophylactic use of antibiotics at the time of a caesarean delivery. Two women died (5%), 14 (38%) women were admitted to intensive care and seven women (19%) had one or more additional severe maternal morbidities, which included three haemorrhagic events, two cardiac arrests, one thrombotic event and one pneumonia. No infants died; however, in those infants whose mother had anaphylaxis before delivery (n=18) there were 7 (41%) neonatal intensive care unit admissions, 3 preterm births and one baby was cooled for neonatal encephalopathy. Conclusions:Anaphylaxis is a rare severe complication of pregnancy and frequently the result of a reaction to antibiotic administration. This study highlights the seriousness of the outcomes of this condition for the mother. The low incidence is reassuring given the large proportion of the pregnant population that receive prophylactic antibiotics during delivery.

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Section: Causal Agentscontrasting

confidence: 99%

The International Network of Obstetric Survey Systems Study of Uterine Rupture: A Descriptive Multicountry Population-based Study

Vandenberghe¹,

Bloemenkamp²,

Berlage³

et al. 2019

Obstetric Anesthesia Digest

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show abstract

“…One important factor is the higher predisposition of women to allergic diseases and their more frequent exposure to NRL (Natural Rubber Latex) items during everyday life and working life [7,13]. Another factor is a greater mucosal contact with latex through barrier contraceptives and during vaginal delivery and vaginal explorations [14][15][16][17][18][19][20][21][22]. In the obstetric population, latex reactions can follow the injection of oxytocin, which raises uterine contraction and may cause the release of latex particles that are deposited in the uterus into the bloodstream [11].…”

Section: Discussionmentioning

confidence: 99%

Anaphylactic latex reaction during anaesthesia: The silent culprit in a fatal case

Turillazzi

Greco

Neri

et al. 2008

Forensic Science International

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“…Many episodes of anaphylactic reactions induced by latex gloves have been reported after normal vaginal delivery or vaginal exploration, most likely provoked by the extensive contact of surgical gloves with highly absorptive membranes. [17][18][19][20][21][22][23] Thus, the most common setting for latex anaphylaxis during surgery may be obstetric and gynecologic procedures, which have been reported to account for approximately 50% of all reactions caused by latex. 15 Latex reactions occur during maintenance anesthesia, usually exhibiting a delay of 30 to 60 min.…”

Section: Discussionmentioning

confidence: 99%