Lateral ventricle choroid plexus papilloma in childhood: management and complications

The formation of cerebrospinal fluid: Nearly a hundred years of interpretations and misinterpretations

“…It is commonly stated that the cause of hydrocephalus is CSF oversecretion. However, other causes are also mentioned, such as arachnoiditis, inflammatory ependymitis, and CSF pathway obstruction caused by the tumorous mass itself, or by its metastases (metastases are usually observed in a cerebello-pontine angle, the third ventricle, the suprasellar region, and the spine: foramen magnum, cervical and lumbo-sacral areas) (Akil et al, 2008;Davson et al, 1987;Nagib and O'Fallon, 2000). Vascularity is increased and the enhancement of the choroid plexus following an injection of gadolinium is very evident in cases of papillomas (Fujimura et al, 2004).…”

“…It was also observed in animals that the amount of proteins in the CSF, as well as the number of white blood cells, is increased in the case of a choroid plexus tumor (Bailey, 1986). Since blood can be found in the CSF, hydrocephalus could develop because of subarachnoid scarring (recurrent bleeding from the tumor) (Barber et al, 2008;Davson et al, 1987;Nagib and O'Fallon, 2000). The ventricle on the side of the lateral ventricular papilloma is usually the larger of the two (Davson et al, 1987) Unfortunately, the treatment of such pathological conditions is not satisfactory.…”

“…Oversecretion of choroid plexus papilloma is shown using the technique of CSF drainage (Fairburn, 1960;Nagib and O'Fallon, 2000;Tamburrini et al, 2006), and a "scientifically acceptable method" of ventriculo-spinal perfusion (Eisenberg et al, 1974;. In some cases, 400 to 960 ml/day have been collected by external drainage, under the conditions of pressure of 5 cm H 2 O (Fairburn, 1960).…”

“…In some cases, 400 to 960 ml/day have been collected by external drainage, under the conditions of pressure of 5 cm H 2 O (Fairburn, 1960). By using CSF drainage, it was determined that more than 2 l of CSF a day could be drained preoperatively (Nagib and O'Fallon, 2000;Tamburrini et al, 2006). However, after a complete tumor resection, in most cases it was observed (cca 2/3 of the cases, according to the literature data) that the CSF extensively drains even more than 72 hours after the operation, and because of this it was necessary to insert a shunt (Lena et al, 1990;Nagib and O'Fallon, 2000).…”

“…By using CSF drainage, it was determined that more than 2 l of CSF a day could be drained preoperatively (Nagib and O'Fallon, 2000;Tamburrini et al, 2006). However, after a complete tumor resection, in most cases it was observed (cca 2/3 of the cases, according to the literature data) that the CSF extensively drains even more than 72 hours after the operation, and because of this it was necessary to insert a shunt (Lena et al, 1990;Nagib and O'Fallon, 2000). Tamburrini et al (2006) have shown that, even after a choroid plexus resection, the CSF drains at the rate of 1000 ml/day.…”