Lateral skull base malignancies

McGrew, Benjamin M.; Jackson, C. Gary; Redtfeldt, Raquel Ann

doi:10.3171/foc.2002.12.5.9

Cited by 12 publications

(14 citation statements)

References 16 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Epithelial, salivary, and mesenchymal tumors have very different natural histories. Previous studies by Manolidis et al2 and McGrew et al5 indicated that local control was better in tumors of mesenchymal origin than it was in tumors of epithelial or salivary origin; however, our data do not support this observation.…”

Section: Discussioncontrasting

confidence: 99%

“…Craniotomy is performed when dural resection is required. Total en bloc resection of the temporal bone and resection of the carotid artery are not performed owing to the high morbidity and low survival rates associated with these procedures 5, 14, 15…”

Section: Discussionmentioning

confidence: 99%

“…Only a few studies have reported large experiences in managing temporal bone and lateral skull base malignancies 2, 4, 5. Important refinements in otologic and neurotologic techniques have occurred since 1975, when Lewis wrote his paper on 100 temporal bone resections 6.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The oncology of otology

et al. 2012

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The oncology of otology

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Although no significant difference in survival was observed, patients with perineural invasion trended toward worse outcomes. These results are consistent with previous studies, which have demonstrated that local control rates are equivalent when cases of perineural involvement are treated with aggressive facial nerve resection and postoperative radiation, 5 and suggest resection is warranted in some cases.…”

Section: Discussionsupporting

confidence: 92%

Outcomes following temporal bone resection

et al. 2010

Self Cite

View full text Add to dashboard Cite

Objectives/Hypothesis To evaluate survival outcomes in patients undergoing temporal bone resection. Study Design Retrospective review. Methods From 2002 to 2009 a total of 65 patients underwent temporal bone resection for epithelial (n = 47) and salivary (n = 18) skull base malignancies. Tumor characteristics, defect reconstruction, and postoperative course were assessed. Outcomes measured included disease-free survival and cancer recurrence. Results The majority of patients presented with recurrent (65%), advanced stage (94%), cutaneous (72%), and squamous cell carcinoma (57%). Thirty-nine patients had perineural invasion (60%) and required facial nerve resection; 16 (25%) had intracranial extension. Local (n = 6), regional (n = 2), or free flap (n = 46) reconstruction was required in 80% of patients. Free flap donor sites included the anterolateral thigh (31%), radial forearm free flap (19%), rectus (35%), and latissimus (4%). The average hospital stay was 4.9 days (range, 1–28 days). The overall complication rate was 15% and included stroke (n = 4), cerebrospinal fluid leak (n = 2), hematoma formation (n = 1), infection (n = 1), flap loss (n = 1), and postoperative myocardial infarction (n = 1). A total of 22 patients (34%) developed cancer recurrence during the follow-up period (median, 10 months), 17 (77%) of whom presented with recurrent disease at the time of temporal bone resection. Two-year disease-free survival was 68%, and 5-year disease-free survival was 50%. Conclusions Aggressive surgical resection and reconstruction is recommended for primary and recurrent skull base malignancies with acceptable morbidity and improved disease-free survival.

show abstract

“…McGrew et al 13 from the Otology 132 group at Nashville, Tennessee, USA published a retrospective review of 95 patients treated for lateral skull base malignancies. The mean age of the patients was 49.4 years.…”

Section: Discussionmentioning

confidence: 99%

Management of lateral skull base tumours

Pai

Moiyadi

Nair

2010

Indian J Surg Oncol

View full text Add to dashboard Cite

Lateral skull base tumours arise from overlying skin, parotid, temporal bone, mandible, muscle or the vasculature and they spread in midst of important neurovascular structures. This makes their diagnosis and management challenging. These tumours are primarily dealt with surgery which can be extensive, functionally disabling and cosmetically disfiguring. Tumour biology, involvement of the internal carotid artery and cranial nerves play key roles in management of these tumours. This review will focus on management of common tumours afflicting the lateral skull base.

show abstract

Lateral skull base malignancies

Cited by 12 publications

References 16 publications

The oncology of otology

The oncology of otology

Outcomes following temporal bone resection

Management of lateral skull base tumours

Contact Info

Product

Resources

About