Background: To investigate the feasibility of using a lateral combined approach with preservation of the extensors and lateral ulnar collateral ligament (LUCL) for exposing the coronal shear fractures of the distal humerus, and to analyze the results of open reduction and internal fixation of these injuries.Methods: 45 patients suffered to coronal shear fractures of the distal humerus with the lateral epicondyle intact were treated with open reduction and internal fixation(ORIF) from January 2013 to August 2020. The fractures were exposed by the lateral combined approach in which the tendons involving the common extensor, the extensor carpi ulnaris and the LUCL was preserved, and the two observing windows formed anterior to and posterior to these tendons and LUCL were used to achieve the fracture reduction. Buried screws with or without plate placed on posterior lateral condyle were used to fix the fragments. The functional outcome of these patients was reviewed and assessed with physical and radiographic examination, range of motion (ROM) measurements, and self-evaluation (Mayo Elbow Performance Index (MEPI) and Disabilities of the Arm, Shoulder, and Hand (DASH) score).Results: 40 patients followed for over one year were included in the final analysis and the mean follow-up duration was 42.10±29.79 months (range, 12-107months). The patients’ mean age was 41.8years (range, 12-74 years). According to Dubberley classification, there were 15 type I, 17 type II and 8 type III fractures. At the final follow-up the average flexion-extension arch was 130.75°(range, 65-150). And the mean pronation and supination was 73.00°(range, 45-80) and 70.63°(range, 40-80), respectively. The mean MEPI score was 87.56(range, 61-97) points, and the results were excellent in 21 patients, good in 13, and fair in 4 and poor in 2. The mean DASH score was 10.59 (range, 0-41.67) points. Neither functional score nor range of movement was associated with age, sex, fracture type, injury type, surgical timing. Conclusions: Reduction and stable fixation with internal fixation for coronal shear fractures of the distal humerus could be achieved by the lateral combined approach. Early functional mobilization could be allowed and then result in satisfactory restoration of elbow function.