“…Furthermore, assessment of treatment outcome is more accurate by comparing natural growth changes in untreated subjects with normal occlusion rather than with controls displaying different types of malocclusion [34]. Therefore, several studies were carried out in the past to investigate longitudinal dental changes in untreated children and adolescents [4,5,7,12,13,15,20,24,27,32,[34][35][36][38][39][40]. However, only a few of them have described dental and soft tissue changes from the deciduous to the permanent dentition [5,7,8,32,[38][39][40].…”