1995
DOI: 10.1016/0967-2109(95)93879-t
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Late results of a prospective study of direct intra-arterial urokinase infusion for peripheral arterial and bypass graft occlusions

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Cited by 26 publications
(12 citation statements)
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“…Due to the varying nature of the embolic debris, not all rescue procedures are successful, sometimes even resulting in amputation. 11 Rickard et al 21 reported a 37% failure rate for attempted lysis after embolic events, and 8.3% of procedures reported by Chalmers et al 22 required thrombectomy.…”
Section: Discussionmentioning
confidence: 99%
“…Due to the varying nature of the embolic debris, not all rescue procedures are successful, sometimes even resulting in amputation. 11 Rickard et al 21 reported a 37% failure rate for attempted lysis after embolic events, and 8.3% of procedures reported by Chalmers et al 22 required thrombectomy.…”
Section: Discussionmentioning
confidence: 99%
“…A report on peri-operative distal embolization following intervention for chronic iliac artery occlusion gives a rate of 2.9% [11]. Some reports on distal embolization during intra-arterial thrombolysis have reported rates of 8.3–24% [12, 13]. A report on the use of the Rotarex catheter for acute and subacute femoro-popliteal artery occlusions indicates that distal embolization during recanalization occurred in 24% of cases [14].…”
Section: Discussionmentioning
confidence: 99%
“…11 Distal embolization during thrombolytic therapy in limb-threatening ischemia is higher. Published studies have reported rates of 3.8 to 37% depending on the risk group [12][13][14] We have found the use of distal protection beneficial in femoropopliteal interventions in three instances: mechanical atherectomy, catheter-directed thrombolysis in acute limb ischemia, and when adjunctive treatment with thrombectomy catheters in performed for acute limb ischemia. 14,15 We also strongly consider use of distal protection in recanalization and standard intervention (angioplasty and stent placement) in certain high-risk patients with limited runoff.…”
Section: Superficial Femoral Arterymentioning
confidence: 98%
“…Several series have described distal embolization during thrombolytic therapy between 3.8 and 37%. 12,13,15 Distal embolization occurs in almost all thrombolysis cases but only becomes apparent as a procedure-related complication in a small subset due to incomplete lysis of fibrinenriched thrombus or due to plaque that becomes dislodged; again, high-risk patients cannot tolerate such hits to limited runoff vessels.…”
Section: Superficial Femoral Arterymentioning
confidence: 99%