Abstract:BACKGROUND
Late relapses of early-stage germ cell tumors are rare. Most patients (-85%) with stage I seminoma are cured by radical orchiectomy. The detection of late relapse is challenging given the relative rarity of this phenomenon, and the fact that patients who have completed surveillance are usually not undergoing regular oncologic workup nor imaging. While many treatment options do exist for a patient with late relapse of seminoma, surgery is typically the mainstay as these tumors are genera… Show more
“…To our knowledge, only 10 cases of metastatic testicular cancer recurrence in the prostate have been reported ( Table 1 ) [ 7 – 15 ]. Five of the cases had late recurrence > 10 years after radical orchiectomy and postoperative adjuvant treatment, and all were detected by physical symptoms.…”
Introduction. Treatment evidence for malignancies metastatic to the prostate in young patients is scarce. Herein, we present a case of prostatic metastasis from testicular cancer treated with induction chemotherapy followed by robot‐assisted radical prostatectomy. Case Presentation. The patient is a 34‐year‐old male who underwent radical orchiectomy for a left testicular tumor two years ago and was diagnosed with a mixed germ cell tumor. He was followed up without adjuvant therapy, but symptoms of dysuria lead to suspicion of a prostate tumor, which was diagnosed by prostate biopsy as seminoma of the prostate. After four cycles of chemotherapy, normalization of tumor markers, and tumor shrinkage on imaging, he underwent robot‐assisted radical prostatectomy. No recurrence has been observed nine months after treatment. Conclusion. In men with a history of testicular cancer presenting with lower urinary tract symptoms, it is important to consider recurrent prostate metastases.
“…To our knowledge, only 10 cases of metastatic testicular cancer recurrence in the prostate have been reported ( Table 1 ) [ 7 – 15 ]. Five of the cases had late recurrence > 10 years after radical orchiectomy and postoperative adjuvant treatment, and all were detected by physical symptoms.…”
Introduction. Treatment evidence for malignancies metastatic to the prostate in young patients is scarce. Herein, we present a case of prostatic metastasis from testicular cancer treated with induction chemotherapy followed by robot‐assisted radical prostatectomy. Case Presentation. The patient is a 34‐year‐old male who underwent radical orchiectomy for a left testicular tumor two years ago and was diagnosed with a mixed germ cell tumor. He was followed up without adjuvant therapy, but symptoms of dysuria lead to suspicion of a prostate tumor, which was diagnosed by prostate biopsy as seminoma of the prostate. After four cycles of chemotherapy, normalization of tumor markers, and tumor shrinkage on imaging, he underwent robot‐assisted radical prostatectomy. No recurrence has been observed nine months after treatment. Conclusion. In men with a history of testicular cancer presenting with lower urinary tract symptoms, it is important to consider recurrent prostate metastases.
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