Late-onset solitary porokeratotic eccrine ostial and dermal duct nevus

Adult-onset porokeratotic eccrine ostial and dermal duct nevus:dermatoscopic findings and treatment with tazarotene

“…The course of PEODDN is chronic. The lesions may remain stable over years [8,10] or be slightly progressive [12]. Our patient experienced spontaneous regression of part of her lesions on the arm and forearm.…”

“…Most cases are present at birth or develop within the first two decades of life [6]. Seven cases [7][8][9][10][11][12][13] had their onset in adulthood, at a mean age of 31 years (range, 18-65). Our patient is therefore the 8 th case of adultonset PEODDN reported in the literature (Table 1).…”

A case of porokeratotic adnexal ostial nevus misdiagnosed as wart

“…PAON typically presents as multiple linear hyperkeratotic papules or punctate pits on extremities, most often at birth or in early childhood. 4,5 Upon review of the literature, at least 81 cases of PEODDN have been reported but many of these cases had their onset at birth, unlike our case. 3 An association with deafness, hemiparesis, hyperthyroidism, polyneuropathy, and seizures has been reported, but the relationship remains uncertain and most patients with PAON are otherwise healthy.…”

“…PAON typically presents as multiple linear hyperkeratotic papules or punctate pits on extremities, most often at birth or in early childhood 4,5 . Upon review of the literature, at least 81 cases of PEODDN have been reported but many of these cases had their onset at birth, unlike our case 3 .…”

“…There are various treatment modalities, including ablative laser therapy, topical steroid, retinoid, emollient, calcipotriol, 5‐fluorouracil, and cryotherapy, but their success is often only partial 10 . CO2 laser and topical retinoids with emollients have consistently yielded clinical improvement to some extent, 4,5 but conservative treatment is the preferred approach. The course of PAON is usually indolent; progressive improvement through a period up to 16 years has been reported 11 .…”