Late onset psychogenic nonepileptic attacks

Abstract

The data suggest a distinct subgroup of patients with late onset psychogenic nonepileptic attacks, in whom psychological trauma related to poor physical health plays a prominent role.

Depression and symptoms affect quality of life in psychogenic nonepileptic seizures

“…25 PNES does occur in the elderly, however, studies reporting outcome measures in the elderly are limited. [26][27][28] Another potential limitation is that the SCL-90 was used as a surrogate for patient symptoms, instead of the AEP used in the Gilliam study. 11 We elected to use the SCL-90 because not all patients with PNES were taking AEDs, the symptoms of which the AEP scale targets specifically.…”

Errors in EEG Interpretation and Misdiagnosis of Epilepsy

“…A robust and replicated finding is that about 30% of patients seen at epilepsy centers for refractory seizures do not have epilepsy [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17]. Remarkably, the proportion of patients misdiagnosed is also similar in patients diagnosed as having posttraumatic epilepsy [18], patients referred directly (without EEG-video monitoring) for vagus nerve stimulation [19] and in patients awarded a ‘seizure alert dog’ [20].…”

187 Early Post-Traumatic Seizures are Associated with Valproic Acid Plasma Concentrations and UGT1A6/CYP2C9 Genetic Polymorphisms in Patients with Severe Traumatic Brain Injury

“…Continuous EEG monitoring reveals that approximately 10% of patients have nonconvulsive seizures, with 30% presenting in the first three days after injury [2,3,35]. It has been recognized that seizure is associated with increased brain edema, excessive metabolic demand, elevated intracranial pressure, and worsened brain atrophy [7,8,36]. Such pathologic process should be diagnosed and controlled as early as possible.…”