Late‐onset lymphopenia during radiation is associated with an increased risk of tumor recurrence in newly diagnosed pediatric medulloblastoma
Holly B. Lindsay,
Michael E. Scheurer,
Anthony K. Allam
et al.
Abstract:BackgroundRecent data found a correlation between lymphopenia occurring early during craniospinal radiation therapy (RT) and risk of disease recurrence in newly diagnosed childhood medulloblastoma. However, the population included patients who received chemotherapy prior to or during RT. Here, we investigate the effect of lymphopenia during RT in patients with newly diagnosed pediatric medulloblastoma who were chemotherapy‐naïve.ProcedureWe analyzed 79 patients with newly diagnosed medulloblastoma (ages 2–21 y… Show more
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