Late onset Ito's nevus

Resende, Cristina; Araújo, Catarina; Vieira, Ana Paula; Brito, Celeste

doi:10.1136/bcr-2013-009746

Cited by 7 publications

(4 citation statements)

References 12 publications

(27 reference statements)

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“…Dermal melanocytoses arising during adulthood are named generally as ‘acquired dermal melanocytosis (ADM)’. Some of these rarely reported lesions resemble naevus of Ito or naevus of Ota in terms of anatomical localization. However, several terms have been used by authors over the past 35 years, starting with ‘acquired, bilateral nevus of Ota‐like macules’ proposed by Hori et al Majority of the reported ADMs involve the face as bilateral blue–brown and grey patches on forehead, eyelids, malar region and nose .…”

Section: Atypical Variants and Presentations Of Dermal Melanocytosesmentioning

confidence: 99%

The spectrum of benign dermal dendritic melanocytic proliferations

Baykal

Yılmaz

Sun

et al. 2019

Acad Dermatol Venereol

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Dermal melanocytoses (DMs) comprise a heterogeneous group of benign lesions, located on skin and mucous membranes, characterized by dendritic melanocytes in the dermis. Although they share common histopathological features, some variants may present only as bluish or grey patches, some only as papules/nodules/plaques and others may show combination of all of these lesions. Despite the fact that blue naevus (BN) is typically characterized with papulonodular lesions, its variants may show all of the aforementioned presentations. Mongolian spot, naevus of Ota and naevus of Ito are patchy DMs distinguished by their specific localizations. Apart from these classical forms, many atypical variants without unique clinicopathological characteristics have been described in the literature making the nomenclature of DMs more complicated. However, congenital dermal melanocytosis and acquired dermal melanocytosis seem to be crucial umbrella terms that encompass all patchy DMs in atypical locations. Papules or subcutaneous nodules on patchy lesions and association of epidermal pigmentation presenting as brownish patches may be encountered as rare features of DMs. On the other hand, delayed‐onset subcutaneous nodules may be typical presentations of melanoma in patchy DMs; therefore, they deserve special attention. Large plaque‐type BN with subcutaneous cellular nodules is a newly described entity, harbouring clinical features of various DMs together and has a high risk of melanoma. The whole spectrum of dermal dendritic melanocytic proliferations is discussed including novelties and controversial issues.

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Section: Atypical Variants and Presentations Of Dermal Melanocytosesmentioning

confidence: 99%

The spectrum of benign dermal dendritic melanocytic proliferations

Baykal

Yılmaz

Sun

et al. 2019

Acad Dermatol Venereol

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“…The late onset of a dermal melanocytosis may indicate other forms of melanocytosis, either congenital or acquired, rather than MBS. Other congenital dermal melanocytosis such as the naevus of Ota and naevus of Ito are usually present at birth while others such as naevus of Hori or blue naevus may appear in childhood or later in life . The histopathology in all these conditions is similar.…”

Section: Discussionmentioning

confidence: 99%

Late onset congenital dermal melanocytosis – ‘Mongolian blue spots’ confused as child abuse: Are there more lessons to be learnt?

Prasad

Tully

2017

J Paediatrics Child Health

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Written and verbal consent was provided by the family for all aspects of this case including but not limited to treatment, investigations and publication. A 10-month-old male Asian infant (known here as Baby A) was brought to the emergency department of a tertiary hospital by his parents with skin discolouration interpreted as new bruising to his back and trunk. The parents described several falls onto a soft play mat while cruising along the edge of a couch over the days preceding presentation. No other history of trauma was offered. The infant had recently been in the care of members of the extended family for 3 days while his mother was hospitalised for an eye condition that compromised her vision. Baby A's mother noticed the new skin marks 4 days after she returned from hospital. No relevant past medical or family history and no history to suggest a coagulation disorder was obtained. The infant was developing normally and able to cruise but not walk independently. The parents described recent verbal conflict surrounding financial matters but there was no history of parental drug or alcohol misuse or family violence. Baby A was not known to protective services.Baby A was thriving, clean and well presented. There were no signs of neglect. Skin examination revealed a Mongolian blue spots (MBS) on Baby A's sacrum. His parents confirmed that this had been present since birth. Superior to the MBS were multiple areas of faint macular homogenous blue/green discolouration associated with multiple small erythematous marks suggestive of superficial abrasions (Fig. 1).To the right of the spine were two parallel linear areas of faint blue/purple discolouration. Two additional areas of faint blue/ purple discolouration were found on the left side of the trunk in the mid-axillary line overlying the lower ribs (Fig. 2). These areas were deemed by the child's parents and multiple medical staff to have the appearance of bruises. The rest of the skin examination and systemic examination revealed normal findings.Owing to the presence of unexplained bruising in an infant less than 1 year of age a full skeletal survey and nucleotide bone scan were performed to exclude or identify occult bony injury. An MRI brain was performed due to concerns from the treating medical team about irritability on a background of possible abusive injury. These investigations revealed no abnormalities. Ophthalmological examination revealed normal retina with no retinal haemorrhages. An extended coagulation profile revealed essentially normal results (mildly depressed factor 13 level).A suspected child abuse and neglect meeting was held, attended by the medical and forensic teams, the police and members of protective services. The opinion of the forensic paediatrician was that the appearance of the bruising was highly suggestive of inflicted injury. Plans were made to seek a protective application through the court; the child was discharged to the care of his parents with an undertaking to ensure his safety with the supervision of child protection servi...

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“…Thus, clinically this entity is distinct from ABNOM/ADM. There are a few reports of late‐onset naevus of Ito as well, with morphology and location similar to classic early‐onset naevus of Ito . Histopathologically, facial and extrafacial ADMs share common features, with melanocytes being largely restricted to the upper and middermis .…”

Section: Description Of the Six Casesmentioning

confidence: 95%