Late-onset diffuse lamellar keratitis 15 years after laser in situ keratomileusis

Abstract

epithelialization; however, this was an incidental finding, and he did not have any systemic signs or symptoms of any rheumatologic conditions or history of HLA-B27related uveitis. Cryopreserved AMT has been described for the following therapeutic indications: persistent epithelial defect and deep corneal ulcer. 7,8 Other indications include Stevens-Johnson syndrome, recurrent pterygium, recurrent Mooren's ulcer, viral keratitis, and sterile corneal melt. 9,10 To date, there has not been a reported case for AMT after corneal melt secondary to collagen crosslinking and TCAT. The use of AMT avoided an emergent corneal transplant surgery for the patient. CONCLUSIONS Corneal melt is a rare and significant complication that can occur after C3R-TCAT. Careful patient selection and counselling are important. The underlying etiology in this case is likely multifactorial. Recognizing and optimizing potential risk factors such as lagophthalmos and blepharitis before surgery will potentially prevent this complication.

Evaluate the Prevalence, Natural Course, and Final Visual Acuity in Patients with Stages III or IV of Diffuse Lamellar Keratitis Following Laser in Situ Keratomileusis

“…Lamellar diffuse keratitis (DLK) is a noninfectious accumulation of inflammatory cells on the submandibular surface that often occurs within the first week after LASIK surgery 1 . Numerous causes have been implicated in the occurrence of DLK, including the presence of particles and debris during surgery 2 , glove powder 3 , red blood cells 4 , tissue particles 1, endotoxins, secretions, and secretions 5 , incidence of corneal epithelial defects and infiltration of betadine solution 6 .…”