Late-onset depression is associated to age-related central auditory processing disorder in an older population in Southern Italy

Lozupone, Madia; Sardone, Rodolfo; Donghia, Rossella; D’Urso, Francesca; Piccininni, Carla; Battista, Petronilla; Gioia, Ilaria Di; Resta, Emanuela; Castellana, Fabio; Lampignano, Luisa; Zupo, Roberta; Bortone, Ilaria; Guerra, Vito; Griseta, Chiara; Seripa, Davide; Solfrizzi, Vincenzo; Giannelli, Gianluigi; Quaranta, Nicola; Logroscino, Giancarlo; Bellomo, Antonello

doi:10.1007/s11357-020-00290-1

Cited by 6 publications

(4 citation statements)

References 47 publications

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“…In these conditions, memory (both working and short) progressively declines. In addition, psychological diseases can further impact memory function, and the elderly are more exposed to this problem [36].…”

Section: Definition Of Hearing Loss and Cognitive Deficit In Elderly Populationmentioning

confidence: 99%

Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations

Bisogno

Scarpa

Girolamo

et al. 2021

Life

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In recent years, there has been increasing research interest in the correlation between hearing impairment and cognitive decline, two conditions that have demonstrated a strong association. Hearing loss appears as a risk factor for cognitive impairment, especially among certain populations, notably nursing home residents. Furthermore, hearing loss has been identified as a modifiable age-related condition linked to dementia, and it has been estimated that midlife hearing loss, if eliminated, might decrease the risk of dementia in the general population. Several mechanisms have been suggested to explain the pathologic connections between hearing loss and dementia; however, clear evidence is missing, and the common pathophysiological basis is still unclear. In this review, we discussed current knowledge about the relationship between hearing loss and dementia, and future perspectives in terms of the effects of hearing rehabilitation for early prevention of cognitive decline.

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Section: Definition Of Hearing Loss and Cognitive Deficit In Elderly Populationmentioning

confidence: 99%

Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations

Bisogno

Scarpa

Girolamo

et al. 2021

Life

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“…8 The HELIAD study in Greece also finds that a low level of education increases risk, as does the Great Age study in southern Italy and the Neurocognitive Study for the Aging (NEUROAGE) in Cyprus. 9,10 Several population-based studies from the Mediterranean areas show that there are risk factors for dementia that are linked to the Mediterranean lifestyle, including diet and metabolic risk factors. Such evidence stems from both the United States and the Mediterranean areas.…”

Section: Epidemiologymentioning

confidence: 99%

“…Lifestyle might help explain the variability: a Mediterranean diet has been found to protect against AD, 7 and the habit of taking a midday nap might also be a factor 8 . The HELIAD study in Greece also finds that a low level of education increases risk, as does the Great Age study in southern Italy and the Neurocognitive Study for the Aging (NEUROAGE) in Cyprus 9,10 . Several population‐based studies from the Mediterranean areas show that there are risk factors for dementia that are linked to the Mediterranean lifestyle, including diet and metabolic risk factors.…”

Section: Epidemiologymentioning

confidence: 99%

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

Sexton

Solis²,

Aharon‐Peretz

et al. 2022

Alzheimer's & Dementia

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As research and services in the Mediterranean region continue to increase, so do opportunities for global collaboration. To support such collaborations, the Alzheimer's Association was due to hold its seventh Alzheimer's Association International Conference Satellite Symposium in Athens, Greece in 2021. Due to the COVID‐19 pandemic, the meeting was held virtually, which enabled attendees from around the world to hear about research efforts in Greece and the surrounding Mediterranean countries. Research updates spanned understanding the biology of, treatments for, and care of people with Alzheimer's disease (AD_ and other dementias. Researchers in the Mediterranean region have outlined the local epidemiology of AD and dementia, and have identified regional populations that may expedite genetic studies. Development of biomarkers is expected to aid early and accurate diagnosis. Numerous efforts have been made to develop culturally specific interventions to both reduce risk of dementia, and to improve quality of life for people living with dementia.

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“… 14 The population-based GreatAGE Study showed that ARHL is associated with depression in later life among Italian community-dwelling older adults. 15 , 16 However, most studies on the associations between ARHL, ARCD, and depression are from Western countries.…”

Section: Introductionmentioning

confidence: 99%

Associations between age-related hearing loss, cognitive decline, and depression in Chinese centenarians and oldest-old adults

Feng

Lin

et al. 2022

Therapeutic Advances in Chronic Disease

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Objective: Age-related hearing loss (ARHL) and age-related cognitive decline (ARCD) are leading causes of disability in older adults. ARHL may increase ARCD risk and cause depression development. This study aimed to explore the associations of ARHL with ARCD and depression in Chinese centenarians and oldest-old adults. Methods: A household survey was conducted on 859 centenarians and oldest-old adults residing in 16 cities and counties in China. Basic information was collected using interview questionnaires, physical examinations, and blood tests conducted by systematically trained local doctors and nurses. Results: In total, 501 (58.3%), 649 (75.6%), and 211 (24.6%) participants had ARHL, ARCD, and depression, respectively. The prevalence of ARCD and depression was significantly higher in participants with ARHL than in those without ARHL (all p < 0.05). Participants with ARHL had significantly lower Mini-Mental State Examination (MMSE) scores indicative of more cognitive decline, and significantly higher 15-item version of the Geriatric Depression Scale (GDS-15) scores suggesting greater levels of depression, than those without ARHL (all p < 0.05). Multivariate logistic regression analyses (Stepwise) indicated that ARHL was significantly and positively associated with ARCD [odds ratio (OR): 1.594, 95% confidence interval (CI): 1.132, 2.245] and depression (OR: 1.623, 95% CI: 1.139, 2.314; all p < 0.05). Multivariate linear regression analyses (Stepwise) indicated that ARHL was significantly and inversely associated with MMSE scores ( B: −2.520, 95% CI: −3.356, −1.684) and significantly and positively associated with GDS-15 scores ( B: 0.713, 95% CI: 0.328, 1.098; all p < 0.05). Conclusion: ARHL is independently associated with ARCD and depression in Chinese centenarians and oldest-old adults.

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Late-onset depression is associated to age-related central auditory processing disorder in an older population in Southern Italy

Cited by 6 publications

References 47 publications

Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations

Hearing Loss and Cognitive Impairment: Epidemiology, Common Pathophysiological Findings, and Treatment Considerations

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

Associations between age-related hearing loss, cognitive decline, and depression in Chinese centenarians and oldest-old adults

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