Topography, bathymetry, regional structural observations, and fault slip measurements support the idea that the Mona rift is an active, offshore extensional structure separating a colliding area (eastern Hispaniola) from a subducting area (northwestern Puerto Rico). Near the city of Aguadilla in northwestern Puerto Rico, paleostress reconstruction through fault slip analysis demonstrates that the Mona rift is opening in an E-W direction. Fault slip analysis also indicates that this opening is oblique in the southern part of the rift. We propose that oblique rifting results from accommodation of E-W extension by oblique right-lateral reactivation of previously mapped, northwest-trending Eocene basement convergent structures (Aguadilla faults, Cerro-Goden fault). The evolution of the stress field during the Miocene and the present E-W opening of the Mona rift support the assumption that the Miocene 25° counterclockwise rotation of Puerto Rico has stopped and that this island is presently moving to the east relative to the colliding Hispaniola.