Late life depression and incident activity limitations: Influence of gender and symptom severity

Carrière, Isabelle; Gutierrez, Laure‐Anne; Pérès, Karine; Berr, Claudine; Barberger‐Gateau, Pascale; Ritchie, Karen; Ancelin, Marie-Laure

doi:10.1016/j.jad.2011.03.020

Cited by 36 publications

(44 citation statements)

References 42 publications

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“…However there was no difference regarding anxiety symptoms or disorders at baseline. Whereas the association between depression and incident disability was previously found to be gender-dependent (Carriere et al, 2011), this appears not to be the case for trait anxiety symptoms or anxiety disorder. However this could be due to smaller sample size, the interaction term failing to reach significance.…”

Section: Strengths and Limitationsmentioning

confidence: 81%

“…While the association between depression and onset of disability in the elderly has been extensively explored (Carriere et al, 2009;Schillerstrom et al, 2008) with depression being confirmed as an independent risk factor even when multiple confounding effects are taken into account (Carriere et al, 2011), less is known about the association between anxiety and disability even though the prevalence of anxiety disorder in the elderly appears to be as high and maybe even higher than that of depression. In the present sample, 2.3% of subjects aged 65 and above had a baseline major depressive episode and 13.2% were classified as having severe depressive symptoms, whereas 14.2% had at least one baseline anxiety disorder; there was a three-fold increase in the prevalence of MDE (6.7%) among subjects with at least one anxiety disorder.…”

Section: Anxiety In the Elderlymentioning

confidence: 99%

“…Mechanisms have previously been reported for the association between depression and incident activity limitations (Carriere et al, 2011) but it is unclear to what extent they also apply to anxiety symptoms and disorder. Anxiety and depression have been shown to have different relationships to mortality (Mykletun et al, 2009) which suggests the mechanisms may differ.…”

Section: Potential Mechanisms For the Relationship Between Anxiety Anmentioning

confidence: 99%

“…While depression has been consistently demonstrated to be an independent risk factor for functional loss in the elderly (Carriere et al, 2011;Carriere et al, 2009;Schillerstrom et al, 2008), little is currently known about the association between anxiety disorders and activity limitations: previous research being largely based on cross-sectional observations (Brenes et al, 2008;Cairney et al, 2008;de Beurs et al, 1999;Porensky et al, 2009;Sareen et al, 2006). To date only two prospective studies have been undertaken.…”

Section: Introductionmentioning

confidence: 99%

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Anxiety symptoms and disorder predict activity limitations in the elderly

Norton

Ancelin

Stewart

et al. 2012

Journal of Affective Disorders

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Section: Strengths and Limitationsmentioning

confidence: 81%

Section: Anxiety In the Elderlymentioning

confidence: 99%

Section: Potential Mechanisms For the Relationship Between Anxiety Anmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Anxiety symptoms and disorder predict activity limitations in the elderly

Norton

Ancelin

Stewart

et al. 2012

Journal of Affective Disorders

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“…31 . Gran parte de los estudios evalúa la contribución de síntomas depresivos sobre la discapacidad, más que una entidad diagnóstica; sin embargo, en estudios como el de Barry, et al 18 , Carriere, et al 20 y Murphy, et al 24 , la depresión fue categorizada por nivel de gravedad, mientras que en otros como el de Li, et al 27 examinan la depresión sub-umbral y los síntomas subsíndrómicos. Por otro lado, en algunos estudios evalúan también el cambio en la condición de depresión 23 , así como la relación bidireccional entre depresión-discapacidad y discapacidad-depresión 28 .…”

Section: Características De Los Estudios Incluidosunclassified

Depresión como predictor de discapacidad en adultos mayores

2017

revsal

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RESUMENIntroducción: Estimaciones prevén que el número de personas con discapacidad aumentará como consecuencia del envejecimiento de la población, ante lo cual es importe identificar los principales factores de riesgo para su prevención. En los adultos mayores (AM) la depresión es una de las alteraciones de salud mental más frecuentes. Objetivo: Describir el estado de la investigación de la depresión como predictor de discapacidad en AM de la comunidad. Metodologia: Revisión de la literatura en bases de datos electrónicas como Pubmed (Medline), Sciencedirect, Ebsco y Lilacs, de estudios longitudinales publicados entre 2007-2017. Resultados: Se seleccionaron 15 artículos, en su mayoría formaron parte de estudios de cohortes de envejecimiento, con participantes con un rango de edad de 55-90 años, con seguimiento de 2 a 10 años. Conclusión: Se presenta un análisis general de las implicaciones de los resultados descritos.Palabras clave: Depresión, discapacidad, envejecimiento, actividades cotidianas, estudios longitudinales ABSTRACT Introduction: Current estimates predict that the number of people with disabilities will increase as a consequence of the aging population, and so it is important to identify the main risk factors for its prevention. In older adults (OA) depression is one of the most frequent mental health alterations. Objective: To describe the status of current research on depression as a predictor of disability in OA in the community. Methodology: Review of the literature in the electronic databases of Pubmed (Medline), Sciencedirect, Ebsco and Lilacs, from longitudinal studies published between 2007-2017. Results: Fifteen articles were selected that were mostly part of cohort aging studies, with participants in the age range of 55-90 years old, and with a follow-up period of 2 to 10 years. Conclusion: A general analysis is presented of the implications of the described results.

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Association of the cumulative burden of late‐life anxiety and depressive symptoms with functional impairment

Simning

Seplaki

2019

Int J Geriat Psychiatry

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Objectives: This study investigates the association of the cumulative burden of anxiety-only, depression-only, and comorbid anxiety and depression symptoms with (a) incident self-care or household activities impairment among those with no baseline self-care or household activities impairment, respectively, or (b) change in status of self-care or household activities impairment among those with baseline impairment. Methods: This study consists of participants (N = 4619) from the National Health and Aging Trends Study, a longitudinal study that examines a nationally representative sample of US adults aged 65 years and older. Outcomes included incident or change in self-care or household activity impairment. Primary independent variables were yearly counts of screening positive for clinically significant symptoms for anxietyonly, depression-only, or co-occurring anxiety and depression. Multivariable logistic regression models examined incident impairment and change in impairment status.Results: Yearly counts of anxiety-only symptoms were associated with incident impairment in self-care and household activities and less improvement in self-care functioning. Yearly counts of depression-only symptoms were associated with incident impairment in self-care and household activities. Yearly counts of co-occurring symptoms of anxiety and depression were associated with incident impairment in self-care and household activities, less improvement in self-care activities, and worsening impairment in household activities. Conclusions:This study finds that the cumulative burden of co-occurring anxiety and depression symptoms is associated with incident impairment in functioning, persistent self-care impairment, and deterioration in household activity impairment.These findings emphasize the importance of managing late-life anxiety and depressive symptoms, which are treatable, frequently co-occur, and contribute to disability.

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Late life depression and incident activity limitations: Influence of gender and symptom severity

Cited by 36 publications

References 42 publications

Anxiety symptoms and disorder predict activity limitations in the elderly

Anxiety symptoms and disorder predict activity limitations in the elderly

Depresión como predictor de discapacidad en adultos mayores

Association of the cumulative burden of late‐life anxiety and depressive symptoms with functional impairment

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