Late effects of high-dose methotrexate in childhood cancer survivors: a Swiss single centre observational study
Kevin Brunold,
Maria Otth,
Katrin Scheinemann
Abstract:Importance
Childhood cancer survivors (CCS) are at risk for late effects of different organ systems. The currently available screening recommendations for those treated with high-dose methotrexate (HD-MTX) are not uniform and the available literature is limited.
Objective
We aim to assess the prevalence and severity of late effects in CCS treated with HD-MTX at a single centre in Switzerland. We focus on organ systems defined at risk by the long-te… Show more
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