Lasting Effects of Surgically Used Topical Vasodilators on DIEP Artery Vascular Function
Jason S. Kofoed,
Fatma B. Tuncer,
Alvin C. Kwok
et al.
Abstract:Background Surgeons routinely apply papaverine, lidocaine, or verapamil to produce acute vasodilation and prevent vasospasms during microvascular surgeries. There is evidence that topical vasodilators may induce postoperative endothelial and smooth muscle dysfunction, which would present after the acute vasodilatory effects of the topical drugs wear off. Therefore, the purpose of the current study was to evaluate the lasting effects of papaverine, lidocaine, and verapamil on human deep inferior epigastric perf… Show more
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