Lassa fever A study of 23 hospital cases

A case report on Lassa fever and hearing loss: A rare occurrence and review of the literature

“…5,6 Other otological manifestations that have been reported include tinnitus, autophony, vertigo, nystagmus and ataxia. 7,8 Deafness is the most common neurological complication of Lassa fever. 3 Varying degrees of deafness occur in approximately one third of cases and in many cases hearing loss is permanent.…”

Occupational hazards in hospitals: risk of infection.

“…This epidemic originated among laboratory staff who had handled the blood and tissues of green monkeys (Cercopithecus aethiops) imported from Uganda, subsequent cases arising among patients with whom these workers had had contact. 94 95 Other viral infections that have appeared in recent years include the Ebola virus, which is highly contagious by contact and has a high mortality rate; Lassa fever,96 97 caused by an adenavirus that is likewise extremely pathogenic for man under hospital and laboratory conditions98 101; haemorrhagic Crimea-Congo fever, reported to have been contracted by hospital personnel after contact with patients' bloodI02; and haemorrhagic fever with renal syndrome reported in laboratory staff who had handled rats spontaneously infected with Hantaan virus. 103 -105 In all such cases special safety measures must be used both in the care of patients and in carrying out laboratory tasks.…”

Hemorrhagic Fever Viruses as Biological Weapons: Medical and Public Health Management

“…52,106,118 Passive immunization has also been associated with enhanced viral replication in experimentally infected animals. 119 The logistics of collection, testing, and storing immune convalescent plasma are formidable.…”

“…50 Like filoviruses, person-to-person transmission of the arenaviruses occurs predominantly by direct contact with infectious blood and bodily fluids. A number of nosocomial outbreaks of Lassa fever [51][52][53] and of New World arenaviruses 54 have occurred via this mechanism. As with filoviruses, person-toperson airborne transmission has been suspected in a few instances.…”