Laser Treatment of Vascular Birthmarks

Alster, Tina S.; Railan, Divya

doi:10.1097/00001665-200607000-00023

Cited by 38 publications

(20 citation statements)

References 35 publications

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“…Yüksek enerjili flaş lambası kullanarak organik rhodamine boyasını enerjize eder ve nonkohorent, darbeli sarı ışık oluşturur 9 . Önceleri kullanılan PDL sistemlerinin ( 577 nm) atım süreleri kısa olduğu için (0,45-1,5 milisaniye) damarlar içinde eritrositlerin koagulasyonuna ve yaklaşık iki hafta süren purpura gelişimine neden olmaktaydı.…”

Section: Darbeli Boya Lazeri (Pulsed Dye Lazer-pdl)unclassified

“…Tedavi sonunda beklenen etki 585-600 nm lazerler için hafif purpura, 595 nm için damarın tamamen kaybolmasıdır 12 . Yeni jenerasyon PDL'ler hemanjioma ve şarap lekeleri gibi konjenital vasküler anomaliler için standart tedavidir 9,13,14 . Bunların dışında fasiyal telenjiektazi, rozasea, telenjiektatik ve venöz bacak varisleri, Civatte'nin poikiloderması ve piyojenik granuloma gibi akkiz vasküler lezyonlarda ve vasküler komponenti olan diğer hastalıklarda da (akne, hipertrofik skarlar, psoriazis ve erken strialar ) kullanılmaktadır 4 .…”

Section: Darbeli Boya Lazeri (Pulsed Dye Lazer-pdl)unclassified

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Vasküler Lezyonlarda Lazer

...

2012

Turkderm

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Özet Sum maryLaser treatment of cutaneous vascular lesions has progressed significantly over the past decades. Lasers and intense pulse light sources (IPL) are based on the principle of selective photothermolysis and can be used for the treatment of many vascular skin lesions. Light devices for vascular lesions include the 532 nm potassium titanyl phosphate laser, 577 to 595 nm pulsed dye laser, intense pulsed light devices, and 800 to 940 nm diode, 755 nm alexandrite and 1,064 nm Nd:YAG lasers. The targeted chromophore for vascular lesions is intravascular oxyhemoglobin. By properly selecting the wavelength which is maximally absorbed by the target and a corresponding pulse duration the target can be preferentially injured without transferring significant amounts of energy to surrounding tissues. Various congenital and acquired lesions can be treated such as hemangiomas, port wine stains, facial telangiectasia and leg veins. Cooling will prevent adverse effects such as pigment alteration and scar formation during therapy. A different number of repeated treatments should be done to achieve complete results of different vascular conditions. This review will discuss the different laser and light-based devices, and provide treatment approach for the management of vascular lesions. Gi riflVasküler lezyonların lazer ile tedavisi dermatoloji pratiğinde en sık uygulanan yöntemlerden birisidir. Son yıllarda lazer teknolojisindeki gelişmelere paralel olarak lazerle tedavi edilebilen vasküler lezyonların spektrumu da genişlemiş ve birçok konjenital ve akkiz vasküler lezyon farklı lazer sistemleri ile tedavi edilebilir hale gelmiştir. Selektif fototermoliz prensibi ile çalışan bu cihazlarda, hedef kromofor tarafından absorbe edilen ışınlar dokularda istenilen biyolojik etkileri ortaya çıkarırken çevre dokuların korunmasına olanak tanımakta, krutlanma, kanama veya skar oluşumu gibi istenmeyen yan etkiler daha az oluşmaktadır. İntravasküler oksihemoglobin (kırmızı lezyonlar), deoksijene hemoglobin (mavi lezyonlar) ve methemoglobin vasküler lezyonların tedavisinde hedeflenen kromoforlardır. Oksihemoglobinin absorbsiyon pikleri 418, 542 ve 577 nm iken www.turk derm.org.tr

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Section: Darbeli Boya Lazeri (Pulsed Dye Lazer-pdl)unclassified

Vasküler Lezyonlarda Lazer

...

2012

Turkderm

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“…[56,57] Pulsed dye laser (PDL) systems (585-595 nm) have long been considered the most vascular specific given the fact that a major absorption peak of oxyhemoglobin occurs at 577 nm. [58,59] Early studies using PDL systems were limited to patients with lighter skin tones before further refinements in laser technology, development of epidermal cooling techniques, and expanded clinical protocols made treatment of darker skin tones safe and effective.…”

Section: Vascular Lesions and Hypertrophic Scarsmentioning

confidence: 99%

“…Transient PIH is the most common adverse effect of PDL treatment of vascular lesions and scars in pigmented skin. [56,73] Although patients with darker skin phototypes are more prone than those with fair skin to develop post-PDL pigmentary changes, epidermal skin cooling techniques can reduce the risk of dyspigmentation.…”

Section: Vascular Lesions and Hypertrophic Scarsmentioning

confidence: 99%

Laser Treatment of Dark Skin

Shah

Alster

2010

American Journal of Clinical Dermatology

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The growing diversification of the patient population coupled with the increasing demand for cosmetic laser rejuvenation has highlighted the need to develop cutaneous laser systems and establish treatment protocols for patients with a wide range of skin conditions and phototypes. Recent technologic advancements have provided viable treatment options to achieve clinical outcomes that were previously only attainable in patients with lighter skin tones. This review provides an updated discussion of the range of laser treatments available for pigmented skin and sets the stage for further advancements. Pigment-specific laser technology with green, red, or near-infrared light targets a variety of pigmented lesions such as lentigines, ephelides, café-au-lait macules, and melanocytic nevi as well as tattoos and unwanted hair. Short-pulsed alexandrite, ruby, and neodymium:yttrium-aluminum-garnet (Nd:YAG) lasers are used for pigmented lesions and tattoos, whereas their longer pulse-width laser counterparts are used for laser-assisted hair removal. Vascular lesions and hypertrophic scars can be treated with a variety of vascular-specific lasers, but it is the pulsed dye laser (PDL) that has long been the gold standard treatment for these lesions due to its high specificity for hemoglobin and its ability to improve skin surface texture in children and adults. Laser skin resurfacing techniques for photodamaged skin and atrophic scars have been optimized with fractional technology to produce excellent clinical outcomes and minimal complication risks. Radiofrequency and nonablative lasers are also used to provide skin tightening and collagen remodeling with virtually no postoperative recovery.

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“…Port wine stains (PWS) are pink to dark‐red, congenital, superficial, vascular malformations consisting of ectatic vessels in the papillary and superficial reticular dermis. With time, the ectatic vessels dilate and the PWS may become dark red and develop exophytic papules or nodules 1,2 . PWS occurs in an estimated 3–5 children per 1000 live births, affecting males and females and all racial groups equally.…”

Section: Introductionmentioning

confidence: 99%

Photodynamic therapy of port-wine stains: Long-term efficacy and complication in Chinese patients

Xiao

Qin

Yuan

et al. 2011

The Journal of Dermatology

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Port-wine stain (PWS) are congenital vascular malformations characterized by ectatic capillaries in the papillary layer of the dermis. They usually appear at birth and tend to become darker and thicker with age. Many clinicians consider the gold standard to treat PWS is pulsed dye laser (PDL) with wavelengths of 585 nm or 595 nm. But PDL is not suitable for patients with Fitzpatrick skin type V or nodular lesions. Vascular-targeted photodynamic therapy (PDT) might be an alternative approach in the treatment of such patients. The objective of this study was to assess the long-term outcomes and complications of PDT therapy of PWS in Chinese patients retrospectively. Patients with PWS who had received PDT therapy in a 5-year period were reviewed. 642 patients and a total of 3066 treatment sessions had been performed with an average of 2.6-8.2 sessions. Over 5% of patients had complete clearing, while 70% of patients had more than 25% of clearing. More than one-quarter of patients (29.8%) experienced a clearing of more than 50%. Ten percent of patients experienced complications (1.4% blistering, 1.2% hypopigmentation, 4.3% hyperpigmentation, 2.2% scabbing, <0.7% prolonged blistering that persisted for >2 months, 0.4% eczema dermatitis, 0.6% photoallergy). Sex, age, number of treatment sessions, average energy density and type of skin were not related to complication rate using the multiple regression analysis. Chinese patients were well responsive to and satisfied with vascular-targeted PDT (Patient Satisfaction Score 7.8). Dark-skinned patients and patients with vascular papules or nodules can be treated with alternative PDT to significant therapeutic effect in Chinese patients even though they experience few complications.

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Laser Treatment of Vascular Birthmarks

Cited by 38 publications

References 35 publications

Vasküler Lezyonlarda Lazer

Vasküler Lezyonlarda Lazer

Laser Treatment of Dark Skin

Photodynamic therapy of port-wine stains: Long-term efficacy and complication in Chinese patients

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