Laser-Time Interaction XII: Photochemical, Photothermal, and Photomechanical

Duncan, Donald D.; Jacques, Steven L.; Johnson, Peter C.

doi:10.21236/ada409012

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…Although Monte Carlo simulation techniques 2 were first introduced in tissue optics in the late 1980s 6 to model the absorption and flux distribution of light in tissue, they are now of increasing importance in the field of biomedical imaging 12,13,15 . An area of growing interest in optical tissue diagnostics and dermatology in particular is polarization imaging 14 .…”

Section: Introductionmentioning

confidence: 99%

Simulating light propagation: towards realistic tissue models

Akarçay

Rička

2011

SPIE Proceedings

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We present a tool for Monte Carlo simulations of polarized light transport in biological tissue samples. This tool can be adapted to various scenarios thanks to a user interface that allows both complex geometrical structures and different illuminating beam profiles to be generated. By combining spheres, cylinders and half-spaces, the user is able to create highly intricate physical models, with each geometrical element able to be assigned its own optical properties: absorption and scattering coefficients, refractive index and scattering law. The scattering law models currently utilized by the tool are the Mie scattering law and the polarized version of the generalized Henyey-Greenstein scattering law: these models can be customized by modifying the appropriate parameters. A tracing method is used to track the propagating photons and handle the reflection/transmission processes (using the Fresnel relations) at interfaces between two different media. Virtual CCDs coupled with polarizers are used to carry out the imaging of the backscattered and transmitted light. The Mueller matrix of the sample can be obtained by measuring the changes that occur in the polarization states (represented by complex Jones vectors) of the propagating photons. The propagating light's temporal and spatial profiles can also be visualized.

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Section: Introductionmentioning

confidence: 99%

Simulating light propagation: towards realistic tissue models

Akarçay

Rička

2011

SPIE Proceedings

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Polarized Light: Electrodynamic Fundamentals

Rička¹,

Frenz²

2010

Optical-Thermal Response of Laser-Irradiated Tissue

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Additional Enhancement of Surface-Enhanced Raman Scattering Spectra of Myoglobin Precipitated under Action of Laser Irradiation on Self-Assembled Nanostructured Surface of Ag Films

Boginskaya,

Slipchenko,

Sedova

et al. 2023

Chemosensors

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The modifications of the microstructure of myoglobin deposited onto SERS-active Ag-based substrates by drying a drop of aqueous solution with and without laser irradiation and the corresponding surface-enhanced Raman scattering (SERS) spectra are studied. It is shown that drying with laser irradiation leads to the formation of protein aggregates of various types, including crystal-like aggregates. It is also shown that after such drying, the aggregates generally have SERS spectra characterized by a change in the position of the vibration bands and the ratios of their amplitudes compared to the spectra of proteins dried without additional treatment. In particular, parts of the SERS spectra of aggregates formed under laser irradiation are characterized by an additional enhancement (up to 100×) compared to the SERS spectra of myoglobin dried in air at room temperature. The crystallization processes were modeled using the results of atomic force microscopy morphology studies of dried myoglobin on the SERS-active substrates to determine the conditions under which crystal-like aggregates start to grow at surface irregularities, specifically those with a volume close to that of the critical-size nucleus, and where the lowest energy of formation occurs. A correlation is established between surface irregularities, the amplitude, and the change in the SERS spectra during the drying of a myoglobin solution sample on a nanostructured Ag-based surface.

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Laser-Time Interaction XII: Photochemical, Photothermal, and Photomechanical

Cited by 3 publications

References 7 publications

Simulating light propagation: towards realistic tissue models

Simulating light propagation: towards realistic tissue models

Polarized Light: Electrodynamic Fundamentals

Additional Enhancement of Surface-Enhanced Raman Scattering Spectra of Myoglobin Precipitated under Action of Laser Irradiation on Self-Assembled Nanostructured Surface of Ag Films

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