Surface energy must in some way be connected to surface chemistry and is therefore an important determinant of a biomaterial's functions. This work elucidates the basic phenomena and wetting mechanisms associated for a widely used bioinert ceramic, magnesia partially stabilized zirconia (MgO-PSZ) following CO 2 laser treatment. Contact angles for a set of test liquids were used to measure the wettability characteristics and to reduce the surface energy of the MgO-PSZ before and after CO 2 laser treatment. CO 2 laser treatment of the MgO-PSZ surface was seen to e ect an improvement in the material's wettability characteristics. Furthermore, it was found that the extent of wettability modi®cation was closely related to the microstructure induced by CO 2 laser radiation on the surface of the MgO-PSZ.
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