Objective: To investigate the effect of laser surface treatment of cast titanium alloy on microstructure and mechanical properties.Methods: Dumbbell-and plate-shaped cast titanium specimens were prepared for mechanical testing and microstructure analysis. After the cast surfaces of each specimen were laser-treated using a dental Nd:YAG laser machine at 240 V and 300 V with and without argon gas shielding, tensile testing and microstructure analysis were conducted.Hardness depth profiles were also made from the cross-section of laser-treated cast specimens. Microstructural and chemical analysis were performed by means of the SEM, XRD, AES and WDS.Results: The results of tensile testing and Vickers hardness depth profiling showed that laser treatment improved the mechanical properties. Bulk microstructure of as-cast titanium was mainly composed of α-grains with acicular and widmanstatten patterns.The laser melted zone was characterized by columnar beta grains. When the emission voltage of laser increased to 300 V, a larger grain size was promoted. The XRD analysis indicated that the beta phase formation was clearly noticeable after laser surface treatment. Supplementary marked peaks of the TiO, TiO 2 and Ti 2 N were detected without argon gas shielding. When argon shielding gas was used, the presence of titanium oxide was significantly reduced and the peaks of titanium nitride disappeared.Significance: Laser treatment on cast titanium surfaces showed significant enhancement of mechanical properties and modification of microstructures, and therefore could produce reliable titanium metal frameworks for dental prostheses.3