Laser surface modification of hydroxyapatite and glass-reinforced hydroxyapatite

Queiroz, Ana Carolina; Santos, J. D.; Vilar, R.; Eugénio, S.; Monteiro, Fernando J.

doi:10.1016/j.biomaterials.2003.11.054

Cited by 29 publications

(19 citation statements)

References 35 publications

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“…It has been reported that HAp containing aspartic acid enhanced osteoblast proliferation and differentiation [45]. Krypton fluoride (KrF) excimer lasers have been used to increase the surface area and to control the surface topography of HAp and the lasermodified material has been found to enhance tissue integration [46,47]. The osteogenic activity of electrically polarized HAp pellets has been previously investigated and the negatively charged HAp surface has been demonstrated to accelerate cell growth on direct contact with bone, whereas the positively charged HAp surface attenuated the osteogenic activity of the material [48][49][50][51].…”

Section: Compatibility With Cells and Tissuesmentioning

confidence: 99%

Modification of Apatite Materials for Bone Tissue Engineering and Drug Delivery Carriers

Matsumoto

Okazaki

Nakahira

et al. 2007

CMC

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Apatite-related calcium phosphate, the main component of biological hard tissue, has good biocompatibility and is an economical material. Methods for the synthesis of apatite materials including hydroxyapatite (HAp) have previously been established. Therefore, for many years, apatite materials have been utilized as substitute materials for bone in orthopedic and dental fields. Such types of conventional substitute materials, which are implanted in the human body, should ostensibly be chemically stable to maintain their quality over time. However, recent advances in tissue engineering have altered this concept. Physicians and researchers now seek to identify materials that alter their properties temporally and spatially to achieve ideal tissue regeneration. In order to use apatite materials for tissue engineering and as drug delivery systems, the materials require both a high affinity for cells, tissues and/or functional molecules (e.g. growth factors and genes) and controllable bioabsorbability. To achieve these properties, various physicochemical modifications of apatite materials have been attempted. In addition, fabrication desiring three-dimensional structures (e.g. size, morphology and porosity) of apatite materials for implant sites could be one of the crucial techniques used to obtain ideal prognoses. In this review, the latest research trends relating to the techniques for the fabrication and modification of apatite materials are introduced.

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Section: Compatibility With Cells and Tissuesmentioning

confidence: 99%

Modification of Apatite Materials for Bone Tissue Engineering and Drug Delivery Carriers

Matsumoto

Okazaki

Nakahira

et al. 2007

CMC

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“…185 The use of gaseous H 2 O in the ambient processing atmosphere has been fairly well documented in terms of laser deposition for coatings, 156,164,167 but in terms of laser ablation as there is little in the literature about surface modification of HA the few existing reports concern the dental application of the modification and removal of dental hard tissue or enamel containing mostly HA. The use of H 2 O is strongly and widely recommended to prevent the accumulation of nonapatite calcium phosphate phases on the irradiated surface.…”

Section: Surface Modification Of Hydroxyapatitementioning

confidence: 99%

Recent developments in processing and surface modification of hydroxyapatite

Norton

Malik

Darr

et al. 2006

Advances in Applied Ceramics

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The present paper reviews the developments in the fields of bioceramic materials and laser surface microstructuring of materials. The clinical success of a bioceramic implant depends largely on the biological response at the implant interface in addition to the sufficiency of the mechanical properties for the application. The use of lasers in the present paper is largely to tailor the topography, surface properties and composition with a view to enhancing the implant biocompatibility. Developments in production methods for hydroxyapatite [HA: Ca 10 (PO 4 ) 6 (OH) 2 ] are also discussed with the advantages of producing nanocrystalline material via emulsion routes. The improved mechanical stability featured by nanocrystalline HA should promote clinical success in further load bearing applications.

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“…Ceramics such as alumina are seeking increased applications as sophisticated engineering materials where surface alterations are vital (Nicolas et al, 1997;Queiroz et al, 2004). The surface modification processes have a substantial effect on the microstructural properties of the ceramics (Gahr and Schneider, 2000;Cappelli et al, 2000).…”

Section: Introductionmentioning

confidence: 99%