Laser–Plasma Interactions

Mihăilescu, I. N.; Hermann, J.

doi:10.1007/978-3-642-13281-0_4

Cited by 9 publications

(8 citation statements)

References 120 publications

(129 reference statements)

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“…This behavior is confirmed by SEM micrographs in which as-deposited films exhibit an improved morphology in the case of ACP/CHT as against ACP/CHT/TC films. Similar features were reported in References [68,69].…”

Section: Wettabilitysupporting

confidence: 89%

Composite Drug Delivery System Based on Amorphous Calcium Phosphate–Chitosan: An Efficient Antimicrobial Platform for Extended Release of Tetracycline

et al. 2021

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One major warning emerging during the first worldwide combat against healthcare-associated infections concerns the key role of the surface in the storage and transfer of the virus. Our study is based on the laser coating of surfaces with an inorganic/organic composite mixture of amorphous calcium phosphate–chitosan–tetracycline that is able to fight against infectious agents, but also capable of preserving its activity for a prolonged time, up to several days. The extended release in simulated fluids of the composite mixture containing the drug (tetracycline) was demonstrated by mass loss and UV–VIS investigations. The drug release profile from our composite coatings proceeds via two stages: an initial burst release (during the first hours), followed by a slower evolution active for the next 72 h, and probably more. Optimized coatings strongly inhibit the growth of tested bacteria (Enterococcus faecalis and Escherichia coli), while the drug incorporation has no impact on the in vitro composite’s cytotoxicity, the coatings proving an excellent biocompatibility sustaining the normal development of MG63 bone-like cells. One may, therefore, consider that the proposed coatings’ composition can open the prospective of a new generation of antimicrobial coatings for implants, but also for nosocomial and other large area contamination prevention.

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Section: Wettabilitysupporting

confidence: 89%

Composite Drug Delivery System Based on Amorphous Calcium Phosphate–Chitosan: An Efficient Antimicrobial Platform for Extended Release of Tetracycline

et al. 2021

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“…Compared to short pulse laser excitation, nanosecond laser ablation takes advantage from the interaction of the laser beam with the vaporized material. This process changes the thermodynamic pathway of the laser-heated matter and leads to larger degrees of atomization and excitation [3]. In the case of ultraviolet (UV) radiation, laser heating occurs exclusively in * Corresponding author: hermann@lp3.univ-mrs.fr a tiny volume close to the sample surface where the plasma density is high enough.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of pressure in a plasma produced by laser ablation of steel

Hermann

Axente

Crăciun

et al. 2018

Spectrochimica Acta Part B: Atomic Spectroscopy

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We investigated the time evolution of pressure in the plume generated by laser ablation with ultraviolet nanosecond laser pulses in a near-atmospheric argon atmosphere. These conditions were previously identified to produce a plasma of properties that facilitate accurate spectroscopic diagnostics. Using steel as sample material, the present investigations benefit from the large number of reliable spectroscopic data available for iron. Recording time-resolved emission spectra with an echelle spectrometer, we were able to perform accurate measurements of electron density and temperature over a time interval from 200 ns to 12 µs. Assuming local thermodynamic equilibrium, we computed the plasma composition within the ablated vapor material and the corresponding kinetic pressure. The time evolution of plume pressure is shown to reach a minimum value below the pressure of the background gas. This indicates that the process of vapor-gas interdiffusion has a negligible influence on the plume expansion dynamics in the considered timescale. Moreover, the results promote the plasma pressure as a control parameter in calibration-free laser-induced breakdown spectroscopy.

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“…where C is a constant (usually C ≈ 1), E esw is the energy content of the shock wave, and ρ 0 is the density of the surrounding atmosphere. ξ is a parameter that accounts for the dimensionality of the propagation, and it is equal to 3 for spherical propagation of the shock wave 5 Points show the velocity calculated as the difference of the radius of the shock between two successive images, divided by the time interval between those images. The curve is the derivative of r(t) from equation (8).…”

Section: Discussionmentioning

confidence: 99%

Identification of discontinuities in plasma plume evolution

2013

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The ejection of material during laser ablation gives rise to the development of discontinuities in the ambient gas. Several of these discontinuities are observed and characterized, including externally and internally propagating shock waves, contact surface, and the ionization front. Qualitative experimental observations and analysis of these discontinuities is presented. Results from shadowgraphy enabled determination of an irradiance threshold between two different ablation mechanisms, and determination of several stages of plasma plume evolution. Consideration of the refractive index as a dynamic sum of the contributions from gas and electrons led to separate identification of ionization front from the contact surface. Furthermore, ionization front was observed to lead the shock wave at the earlier stage of the ablation.

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Laser–Plasma Interactions

Cited by 9 publications

References 120 publications

Composite Drug Delivery System Based on Amorphous Calcium Phosphate–Chitosan: An Efficient Antimicrobial Platform for Extended Release of Tetracycline

Composite Drug Delivery System Based on Amorphous Calcium Phosphate–Chitosan: An Efficient Antimicrobial Platform for Extended Release of Tetracycline

Evaluation of pressure in a plasma produced by laser ablation of steel

Identification of discontinuities in plasma plume evolution

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