Laser-induced fluorescence diagnosis of stomach tumor

Loshchenov, Maxim; Levkin, V.V.; Kalyagina, Nina; Linkov, Kirill G.; Kharnas, Sergey S.; Efendiev, Kanamat; Kharnas, Pavel; Loschenov, Victor B.

doi:10.1007/s10103-020-02963-x

Cited by 7 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The peak wavelength of the laser (635 nm) was chosen as the best trade-o (i) using only one fluorescence excitation light source; (ii) extending tissue dep (compared to blue light excitation); and (iii) enabling the detection of three d (Ce6, PpIX, and MB). Regarding Ce6, despite its second main absorption pea gion of 660 nm, its molar extinction at 635 nm is still about 5000 cm −1 /M (whic The imaging system has already been tested in clinical settings and has shown that it detects fluorescence in real conditions with sufficient sensitivity [29,30]. In the present work, the experiment was designed to be as close as possible to the picture obtained in real conditions.…”

Section: Bimodal Endoscopic System and Image Acquisition Protocolmentioning

confidence: 94%

“…A bimodal video system with a rigid endoscope featuring a 45-degree bevel was used for image acquisition. The main technical features of this device, developed by our team, are provided in [29,30]. Briefly, it consists of two cameras (a highly sensitive black-andwhite digital CCD with an optical filter and a color camera), beam splitter, cystoscope, and illuminating devices (WL source, laser).…”

Section: Bimodal Endoscopic System and Image Acquisition Protocolmentioning

confidence: 99%

“…However, it appears that this low level of absorption is sufficient to be detected in clinics by specific sensitive devices or for antibacterial use [31][32][33][34][35][36][37]. PpIX has a pronounced maximum at 635 nm (Figure 3), and examples of its detection in different organs being excited at 630-635 nm can be found in [13,14,29,30].…”

Section: Bimodal Endoscopic System and Image Acquisition Protocolmentioning

confidence: 99%

See 2 more Smart Citations

Validation of a White Light and Fluorescence Augmented Panoramic Endoscopic Imaging System on a Bimodal Bladder Wall Experimental Model

Moskalev,

Kalyagina,

Kozlikina

et al. 2024

Photonics

Self Cite

View full text Add to dashboard Cite

Background: Fluorescence visualization of pathologies, primarily neoplasms in human internal cavities, is one of the most popular forms of diagnostics during endoscopic examination in medical practice. Currently, visualization can be performed in the augmented reality mode, which allows to observe areas of increased fluorescence directly on top of a usual color image. Another no less informative form of endoscopic visualization in the future can be mapping (creating a mosaic) of the acquired image sequence into a single map covering the area under study. The originality of the present contribution lies in the development of a new 3D bimodal experimental bladder model and its validation as an appropriate phantom for testing the combination of bimodal cystoscopy and image mosaicking. Methods: An original 3D real bladder-based phantom (physical model) including cancer-like fluorescent foci was developed and used to validate the combination of (i) a simultaneous white light and fluorescence cystoscopy imager with augmented reality mode and (ii) an image mosaicking algorithm superimposing both information. Results: Simultaneous registration and real-time visualization of a color image as a reference and a black-and-white fluorescence image with an overlay of the two images was made possible. The panoramic image build allowed to precisely visualize the relative location of the five fluorescent foci along the trajectory of the endoscope tip. Conclusions: The method has broad prospects and opportunities for further developments in bimodal endoscopy instrumentation and automatic image mosaicking.

show abstract

Section: Bimodal Endoscopic System and Image Acquisition Protocolmentioning

confidence: 94%

Section: Bimodal Endoscopic System and Image Acquisition Protocolmentioning

confidence: 99%

Section: Bimodal Endoscopic System and Image Acquisition Protocolmentioning

confidence: 99%

See 1 more Smart Citation

Validation of a White Light and Fluorescence Augmented Panoramic Endoscopic Imaging System on a Bimodal Bladder Wall Experimental Model

Moskalev,

Kalyagina,

Kozlikina

et al. 2024

Photonics

Self Cite

View full text Add to dashboard Cite

show abstract

“…Low power He-Ne lasers have been used clinically to prevent as well as treat skin infections and promote wound healing. However, because the depth for the function of the low-level laser is shallow[ 49 ], causing it have to have less effect on deep tissue, this approach needs to be combined with other physical therapies such as electrical stimulation and HBO therapy if the flap is thick.…”

Section: Phototherapymentioning

confidence: 99%

Non-invasive physical therapy as salvage measure for ischemic skin flap: A literature review

Zheng

Yin

et al. 2021

WJCC

View full text Add to dashboard Cite

This review focuses on the available evidence regarding the molecular mechanisms and treatment potential of several non-surgical physical therapies for managing flap ischemia to propose a non-invasive, economical, and simple treatment to improve flap survival. A review of the literature was conducted on the topics of various non-invasive methods for the treatment of ischemic necrosis of the distal end of the flap between 1988 and 2019. A total of 52 published studies were reviewed on the applications of hyperbaric oxygen therapy, electrical stimulation therapy, heat stress pretreatment, phototherapy, and vibration therapy to manage skin flap necrosis. The underlying molecular mechanisms of these physical therapies on revitalizing the dying skin flaps were discussed and preliminary clinical uses of these therapies to salvage the necrotic skin flaps were pooled and summarized for clarifying the safety and feasibility of these methods. Various physical therapy regimens have been ushered to manage necrotic development in cutaneous flaps. With the refinement of these new technologies and enhancement of related basic science research on vascular revitalization, the prevention and treatment of flap ischemia will enter a new era.

show abstract

“…Fluorescent probes have different principles, such as EPR effects (enhanced permeability and retention) and antigen-antibody reactions. To date, fluorescence imaging has exhibited promising advantages in various tumors, such as brain tumors ( 5 ), breast cancer ( 6 ), and gastric cancer ( 7 ).…”

Section: Introductionmentioning

confidence: 99%

Progresses in Fluorescence Imaging Guidance for Bone and Soft Tissue Sarcoma Surgery

Chen

Huang

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

R0 surgical resection is the preferred treatment for bone and soft tissue sarcoma. However, there is still a lack of precise technology that can visualize bone and soft tissue sarcoma during surgery to assist the surgeon in judging the tumor surgical boundary. Fluorescence imaging technology has been used in the diagnosis of cancer. It is a simple and essentially safe technique that takes no additional time during the operation. Intraoperative fluorescence imaging has potential application prospects in assisting the surgeons in judging the tumor boundary and improving the accuracy of surgical resection. This review mainly starts with clinical studies, animal experimentation, and newly designed probes of intraoperative fluorescence imaging of bone and soft tissue sarcoma, to appraise the application prospects of fluorescence imaging technology in bone and soft tissue sarcoma.

show abstract

Laser-induced fluorescence diagnosis of stomach tumor

Cited by 7 publications

References 21 publications

Validation of a White Light and Fluorescence Augmented Panoramic Endoscopic Imaging System on a Bimodal Bladder Wall Experimental Model

Validation of a White Light and Fluorescence Augmented Panoramic Endoscopic Imaging System on a Bimodal Bladder Wall Experimental Model

Non-invasive physical therapy as salvage measure for ischemic skin flap: A literature review

Progresses in Fluorescence Imaging Guidance for Bone and Soft Tissue Sarcoma Surgery

Contact Info

Product

Resources

About