The wastewater from the production of polytetrahydrofuran (PolyTHF) was treated with union between of the extraction method and adsorption method. The results showed that using chloroform as extraction agent, CODCr removal rate could reach as high as 75%, then the treatment of wastewater was treated by adsorption method, which meet the national level of discharging standard, CODCr removal could reach at 100mg/L.